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Literature DB >> 7378141

Intravesical therapy with adriamycin in patients with superficial bladder tumors.

F Edsmyr, T Berlin, J Boman, M Duchek, P L Esposti, H Gustafsson, H Wijkström, L G Collste.

Abstract

An 80-mg dose of adriamycin was given intravesically once a month to 58 patients with superficial transitional cell tumor of the bladder. Complete cytological remission was achieved in all 11 patients with previously untreated, flat carcinoma in situ lesions. In 19 carcinoma in situ patients, who were previously treated by other means, cytological remission occurred in 74%. In T1 and T2 papillary tumor remission occurred in 65 and 20%, respectively. Minor local side effects were observed.

Entities: Chemical Disease Species

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Doxorubicin

Year: 1980 PMID： 7378141 DOI： 10.1159/000473310

Source DB: PubMed Journal: Eur Urol ISSN： 0302-2838 Impact factor: 20.096

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Cited

14 in total

1. Chemosensitivity study of urological malignancies using a novel dye-exclusion method.

Authors: K Naito; H Hisazumi; S Mihara; T Asari; K Kobashi; T Amano; T Uchibayashi
Journal: Cancer Chemother Pharmacol Date: 1987 Impact factor: 3.333

2. Verapamil enhanced in vitro chemosensitivity of a murine bladder carcinoma, FCB.

Authors: R J Ballou; W G Simpson; J I Harty; M T Tseng
Journal: Urol Res Date: 1986

3. Approaches to the treatment of bladder cancer at Stanford.

Authors: F M Torti
Journal: Cancer Chemother Pharmacol Date: 1987 Impact factor: 3.333

Review 4. Current diagnostic and therapeutic methods in the treatment of vesical tumours.

Authors: D Frang; L Somogyi; A Jilling
Journal: Int Urol Nephrol Date: 1988 Impact factor: 2.370

Review 5. Intravesical chemotherapy in the United States. An overview.

Authors: J T Spaulding
Journal: Cancer Chemother Pharmacol Date: 1983 Impact factor: 3.333

6. Comparative analysis of short-term and long-term prophylactic intravesical chemotherapy of superficial bladder cancer. Prospective, randomized, controlled studies of the Japanese Urological Cancer Research Group.

Authors: H Akaza; S Isaka; K Koiso; T Kotake; T Machida; A Maru; Y Matsumura; T Niijima; K Obata; H Ohe
Journal: Cancer Chemother Pharmacol Date: 1987 Impact factor: 3.333

Intravesical therapy with adriamycin in patients with superficial bladder tumors.

1. Chemosensitivity study of urological malignancies using a novel dye-exclusion method.

2. Verapamil enhanced in vitro chemosensitivity of a murine bladder carcinoma, FCB.

3. Approaches to the treatment of bladder cancer at Stanford.

Review 4. Current diagnostic and therapeutic methods in the treatment of vesical tumours.

Review 5. Intravesical chemotherapy in the United States. An overview.

6. Comparative analysis of short-term and long-term prophylactic intravesical chemotherapy of superficial bladder cancer. Prospective, randomized, controlled studies of the Japanese Urological Cancer Research Group.

7. Sequential instillation therapy with mitomycin C and adriamycin for superficial bladder tumors.

8. Prophylactic use of topical adriamycin after transurethral resection of transitional cell bladder tumours.

9. Organ distribution of Adriamycin after intravesical instillation with or without Tween 80 in the rat.

10. Effects of N-trifluoroacetyladriamycin-14-valerate (AD-32) on human bladder tumor cell lines.