Literature DB >> 7377741

Calcium metabolism in a fatal case of sodium fluoride poisoning.

E Simpson, L G Rao, R M Evans, W Wilkie, J C Rodger, A Lakhani.   

Abstract

A patient was admitted to a district general hospital within an hour of ingesting a fatal dose of sodium fluoride. The results of laboratory investigations, together with some in vitro findings, support the hypothesis that the hypocalcaemia of fluoride poisoning is the result of fluorapatite formation and not calcium fluoride precipitation, and that its persistence reflects the severity of the calcium deficit and not an inhibitoin of normal homeostatic mechanisms. It is suggested that the role of renal clearance of fluoride may be more important than had been realised hitherto.

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Year:  1980        PMID： 7377741     DOI： 10.1177/000456328001700102

Source DB:  PubMed          Journal:  Ann Clin Biochem        ISSN： 0004-5632            Impact factor:   2.057


  7 in total

1.  Case files of the Toxikon Consortium in Chicago: survival after intentional ingestion of hydrofluoric acid.

Authors:  Patrick M Whiteley; Steven E Aks
Journal:  J Med Toxicol       Date:  2010-09

2.  Red blood cell glucose metabolism in human chronic fluoride toxicity.

Authors:  D Saralakumari; P R Rao
Journal:  Bull Environ Contam Toxicol       Date:  1991-12       Impact factor: 2.151

Review 3.  Acute fluoride toxicity. Pathophysiology and management.

Authors:  M E McIvor
Journal:  Drug Saf       Date:  1990 Mar-Apr       Impact factor: 5.606

4.  An experimental study on the treatment of hydrofluoric acid burns.

Authors:  K Kono; Y Yoshida; M Watanabe; Y Tanioka; T Dote; Y Orita; Y Bessho; J Yoshida; Y Sumi; K Umebayashi
Journal:  Arch Environ Contam Toxicol       Date:  1992-05       Impact factor: 2.804

5.  Parathyroid glands, calcium, and vitamin D in experimental fluorosis in pigs.

Authors:  L Andersen; A Richards; A D Care; H M Andersen; J Kragstrup; O Fejerskov
Journal:  Calcif Tissue Int       Date:  1986-04       Impact factor: 4.333

6.  The effect of intravenous sodium fluoride and synthetic salmon calcitonin on plasma total calcium, inorganic phosphate, and ionic fluoride.

Authors:  P A Monsour; J R Smid; B J Kruger
Journal:  Calcif Tissue Int       Date:  1987-08       Impact factor: 4.333

Review 7.  Toxicity of fluoride: critical evaluation of evidence for human developmental neurotoxicity in epidemiological studies, animal experiments and in vitro analyses.

Authors:  Sabine Guth; Stephanie Hüser; Angelika Roth; Gisela Degen; Patrick Diel; Karolina Edlund; Gerhard Eisenbrand; Karl-Heinz Engel; Bernd Epe; Tilman Grune; Volker Heinz; Thomas Henle; Hans-Ulrich Humpf; Henry Jäger; Hans-Georg Joost; Sabine E Kulling; Alfonso Lampen; Angela Mally; Rosemarie Marchan; Doris Marko; Eva Mühle; Michael A Nitsche; Elke Röhrdanz; Richard Stadler; Christoph van Thriel; Stefan Vieths; Rudi F Vogel; Edmund Wascher; Carsten Watzl; Ute Nöthlings; Jan G Hengstler
Journal:  Arch Toxicol       Date:  2020-05-08       Impact factor: 5.153
  7 in total

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