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Literature DB >> 7376944

Prevention of recurrence of spontaneous subarachnoid haemorrhage by tranexamic acid.

Abstract

Tranexamic acid as an antifibrinolytic agent has been investigated in a controlled study in patients with recent subarachnoid haemorrhage. It is concluded that tranexamic acid improves neither rebleeding rates, nor mortality. Predominantly thrombotic complications have been noted as a more serious side effect of tranexamic acid.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1980 PMID： 7376944 DOI： 10.1007/bf01400945

Source DB: PubMed Journal: Acta Neurochir (Wien) ISSN： 0001-6268 Impact factor: 2.216

20 in total

1. xi-Aminocaproic acid: an inhibitor of plasminogen activation.

Authors: N ALKJAERSIG; A P FLETCHER; S SHERRY
Journal: J Biol Chem Date: 1959-04 Impact factor: 5.157

2. [Rapid physiological coagulation method in determination of fibrinogen].

Authors: A CLAUSS
Journal: Acta Haematol Date: 1957-04 Impact factor: 2.195

3. Effect of tranexamic acid on rebleeding after subarachnoid hemorrhage: a double-blind controlled clinical trial.

Authors: J van Rossum; A R Wintzen; L J Endtz; J H Schoen; H de Jonge
Journal: Ann Neurol Date: 1977-09 Impact factor: 10.422

4. Earlier operation and antifibrinolytic therapy in the management of aneurysmal subarachnoid haemorrhage. Review of recent experience in Tasmania.

Authors: G Corkill
Journal: Med J Aust Date: 1974-03-30 Impact factor: 7.738

5. Arteriopathic complications during treatment of subarachnoid hemorrhage with epsilon-aminocaproic acid.

Authors: V K Sonntag; B M Stein
Journal: J Neurosurg Date: 1974-04 Impact factor: 5.115

6. Antifibrinolytic therapy for intracranial aneurysms.

Authors: S Mullan; J Dawley
Journal: J Neurosurg Date: 1968-01 Impact factor: 5.115

7. Glomerular capillary thrombosis and acute renal failure after epsilon-amino caproic acid therapy.

Authors: C Charytan; D Purtilo
Journal: N Engl J Med Date: 1969-05-15 Impact factor: 91.245

8. The use of antifibrinolytic substances in ruptured intracranial aneurysms.

Authors: G Norlén; C A Thulin
Journal: Neurochirurgia (Stuttg) Date: 1969-05

9. Role of urokinase and tissue activator in sustaining bleeding and the management thereof with EACA and AMCA.

Authors: L Andersson; I M Nilsoon; S Colleen; B Granstrand; B Melander
Journal: Ann N Y Acad Sci Date: 1968-06-28 Impact factor: 5.691

10. AMCA (aminomethyl cyclohexane carboxylic acid, Cyklo-kapron) a potent haemostatic agent in urinary tract bleeding.

Authors: L Andersson; I M Nilsson
Journal: Scand J Urol Nephrol Date: 1969

12 in total

Review 1. Antifibrinolytic agents in subarachnoid haemorrhage.

Authors: K W Lindsay
Journal: J Neurol Date: 1987-01 Impact factor: 4.849

2. Benefits and risks of antifibrinolytic therapy in the management of ruptured intracranial aneurysms. A double-blind placebo-controlled study.

Authors: S A Tsementzis; E R Hitchcock; C H Meyer
Journal: Acta Neurochir (Wien) Date: 1990 Impact factor: 2.216

3. Letter to the editors of acta neurochirurgica. Management of patients with subarachnoid haemorrhage with tranexamic acid.

Authors: H Fodstad; C A Thulin
Journal: Acta Neurochir (Wien) Date: 1980 Impact factor: 2.216

4. Fibrinolytic activity after subarachnoid haemorrhage and the effect of tranexamic acid.

Authors: S A Tsementzis; W P Honan; S Nightingale; E R Hitchcock; C H Meyer
Journal: Acta Neurochir (Wien) Date: 1990 Impact factor: 2.216

Review 5. Clinical application of inhibitors of fibrinolysis.

Authors: M Verstraete
Journal: Drugs Date: 1985-03 Impact factor: 9.546

Review 6. Tranexamic acid: a review of its use in surgery and other indications.

Authors: C J Dunn; K L Goa
Journal: Drugs Date: 1999-06 Impact factor: 9.546

Review 7. Antifibrinolytic treatment in subarachnoid haemorrhage: present state.

Authors: H Fodstad
Journal: Acta Neurochir (Wien) Date: 1982 Impact factor: 2.216

Review 8. Antifibrinolytic therapy to prevent early rebleeding after subarachnoid hemorrhage.

Authors: Mark Chwajol; Robert M Starke; Grace H Kim; Stephan A Mayer; E Sander Connolly
Journal: Neurocrit Care Date: 2008 Impact factor: 3.210

9. Rebleeding, ischaemia and hydrocephalus following anti-fibrinolytic treatment for ruptured cerebral aneurysms: a retrospective clinical study.

Authors: G Pinna; A Pasqualin; C Vivenza; R Da Pian
Journal: Acta Neurochir (Wien) Date: 1988 Impact factor: 2.216

10. Comparative clinical trial of epsilon amino-caproic acid and tranexamic acid in the prevention of early recurrence of subarachnoid haemorrhage.

Authors: U M Chowdhary; K Sayed
Journal: J Neurol Neurosurg Psychiatry Date: 1981-09 Impact factor: 10.154