Literature DB >> 7375938

Evidence for a vesicular transport mechanism in hepatocytes for biliary secretion of immunoglobulin A.

R H Renston, A L Jones, W D Christiansen, G T Hradek, B J Underdown.   

Abstract

Quantitative electron microscopic autoradiography and diaminobenzidine cytochemistry provide evidence for an uptake and vesicular transport mechanism for iodine-125-labeled immunoglobulin A from plasma to bile by hepatocytes in vivo. The data confirm the existence of a hepatobiliary pathway for secretion of immunoglobulin A into the intestine and are consistent with a vesicular transport mechanism for biliary proteins within liver parenchymal cells.

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Year:  1980        PMID： 7375938     DOI： 10.1126/science.7375938

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  45 in total

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Authors:  Y J Gan; J Chodosh; A Morgan; J W Sixbey
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Review 4.  Receptor-mediated transport of peptide hormones and its importance in the overall hormone disposition in the body.

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Journal:  Pharm Res       Date:  1989-03       Impact factor: 4.200

5.  Uptake and distribution of hepatocyte growth factor in normal and regenerating adult rat liver.

Authors:  M L Liu; W M Mars; R Zarnegar; G K Michalopoulos
Journal:  Am J Pathol       Date:  1994-01       Impact factor: 4.307

6.  In vivo experiments involving secretory component in the rat hepatic transfer of polymeric IgA from blood into bile.

Authors:  I Lemaître-Coelho; G A Altamirano; C Barranco-Acosta; R Meykens; J P Vaerman
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7.  IgA antibodies in rat bile inhibit cholera toxin-induced secretion in ileal loops in situ.

Authors:  T Tamaru; W R Brown
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8.  Gall bladder: the predominant source of bile IgA in man?

Authors:  D A Vuitton; E Seilles; P Claude; P Sava; D L Delacroix
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9.  Transport of infectious reovirus into bile: class II major histocompatibility antigen-bearing cells determine reovirus transport.

Authors:  D H Rubin; T Costello; C L Witzleben; M I Greene
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10.  Immunoglobulin A stimulates growth of the extrahepatic bile duct in BALB/c mice.

Authors:  S Fallon-Friedlander; J R Boscamp; R Morecki; F Lilly; M S Horwitz; J H Glaser
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