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Literature DB >> 737547

Mean wall thickness of trabecular bone packets in the human iliac crest: changes with age.

Abstract

The mean wall thickness (MWT) of packets of trabecular bone was measured in undecalcified iliac crest bone samples of 36 normal subjects (14 female and 22 male) under polarized light. The mean wall thickness was 49.7 +/- 8.7 microns at a mean age of 50.9 years. There existed a significant decrease of MWT with advancing age. With an appositional rate of 0.72 micron/day, the mean formation time of iliac trabecular bone packets is 69 days. The decrease of MWT with age corresponds to a decrease in bone formation at the basic multicellular unit (BMU) level with aging and can partly explain the physiological senile osteopenia.

Entities: Disease Species

Mesh：

Year: 1978 PMID： 737547 DOI： 10.1007/bf02013227

Source DB: PubMed Journal: Calcif Tissue Res ISSN： 0008-0594

10 in total

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10 in total

86 in total

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Authors: Stavros C Manolagas
Journal: Endocr Rev Date: 2010-01-05 Impact factor: 19.871

Mean wall thickness of trabecular bone packets in the human iliac crest: changes with age.

1. Mean formation time of human osteons.

2. Variations in cross-section area of rib cortex with age.

3. Physiological senile involution and pathological rarefaction of bone. Quantitative and comparative histological data.

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6. The cancellous bone of the iliac crest.

7. A quantitative histological study on bone resorption in human cancellous bone.

Review 8. Bone dynamics in metabolic bone disease.

9. Quantitative structural analysis of human cancellous bone.

10. A quantitative histological study on bone formation in human cancellous bone.

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Review 10. From estrogen-centric to aging and oxidative stress: a revised perspective of the pathogenesis of osteoporosis.