Literature DB >> 73740

Serum-alpha1-fetoprotein in patients with testicular tumours.

J Kohn, A H Orr, T J McElwain, M Bentall, M J Peckham.   

Abstract

Serum-alpha1-fetoprotein (A.F.P.) was assayed in 88 men with testicular teratomas and 34 with seminomas. 61% of teratoma patients with clinically evident disease had serum-A.F.P. greater than 25 ng/ml, whilst it is highly unlikely that any patient with a pure seminoma had a titre above this level. A.F.P. concentrations correlated with response to radiotherapy and chemotherapy and predicted relapse in some patients. Serum-A.F.P. should be measured in all patients with testicular tumours.

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Year:  1976        PMID: 73740     DOI: 10.1016/s0140-6736(76)92524-1

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  7 in total

1.  Advances in pathology and immunocytochemistry.

Authors:  E Heyderman
Journal:  J R Soc Med       Date:  1985       Impact factor: 5.344

2.  Sacrococcygeal teratoma and normal alphafetoprotein concentration in amniotic fluid.

Authors:  M Szabó; P Varga; A Zalatnai; J Hidvégi; Z Tóth; Z Papp
Journal:  J Med Genet       Date:  1985-10       Impact factor: 6.318

3.  The detection and measurement of oncodevelopmental proteins in gynecological malignant disease.

Authors:  C Cerni; G Tatra
Journal:  Arch Gynecol       Date:  1982

4.  Alpha-fetoprotein, alpha-1-antitrypsin, and transferrin in gonadal yolk-sac tumours.

Authors:  J O Beilby; C H Horne; G D Milne; C Parkinson
Journal:  J Clin Pathol       Date:  1979-05       Impact factor: 3.411

Review 5.  The detection and evaluation of human tumor metastases.

Authors:  D J Laurence; A M Neville
Journal:  Cancer Metastasis Rev       Date:  1983       Impact factor: 9.264

6.  Serum Tumour Markers in Testicular Germ Cell Tumours: Frequencies of Elevated Levels and Extents of Marker Elevation Are Significantly Associated with Clinical Parameters and with Response to Treatment.

Authors:  Klaus-Peter Dieckmann; Hanna Simonsen-Richter; Magdalena Kulejewski; Petra Anheuser; Henrik Zecha; Hendrik Isbarn; Uwe Pichlmeier
Journal:  Biomed Res Int       Date:  2019-05-28       Impact factor: 3.411

7.  Brain metastases in malignant teratoma: a review of four years' experience and an assessment of the role of tumour markers.

Authors:  S B Kaye; K D Bagshawe; T J McElwain; M J Peckham
Journal:  Br J Cancer       Date:  1979-03       Impact factor: 7.640

  7 in total

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