Literature DB >> 7373331

Patient-specific anti=acetylcholine receptor antibody patterns in myasthenia gravis.

T Savage-Marengo, R Harrison, G G Lunt, P O Behan.   

Abstract

Anti-acetylcholine receptor (AChR) antibodies have been determined in the sera of ten myasthenic patients over a period of several months which in each case included a series of plasma-exchanges coupled with immunosuppressive therapy. The ratio of anti-(extra-junctional rat AChR): anti-(human AChR) antibody titres was found to vary with the patient but to be constant for a given patient over the period of study. Similar indications of a patient-specific anti-AChR antibody pattern were obtained by using junctional as well as extra-junctional rat AChR and also by precipitation of human AChR in the presence of excess antiserum. Individual anti-AChR antibody patterns may have relevance to the varying courses taken by myasthenia gravis in different patients.

Entities:  

Mesh：

Substances：

Year:  1980        PMID： 7373331      PMCID： PMC490535          DOI： 10.1136/jnnp.43.4.316

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN： 0022-3050            Impact factor:   10.154


  11 in total

1.  Determination of acetylcholine receptor antibody in myasthenia gravis: clinical usefulness and pathogenetic implications.

Authors:  A K Lefvert; K Bergström; G Matell; P O Osterman; R Pirskanen
Journal:  J Neurol Neurosurg Psychiatry       Date:  1978-05       Impact factor: 10.154

2.  Plasmapheresis and immunosuppressive drug therapy in myasthenia gravis.

Authors:  P C Dau; J M Lindstrom; C K Cassel; E H Denys; E E Shev; L E Spitler
Journal:  N Engl J Med       Date:  1977-11-24       Impact factor: 91.245

3.  Rat or human acetylcholine-receptor antigen for investigation of myasthenia gravis?

Authors:  T S Marengo; R Harrison; G G Lunt; P O Behan
Journal:  Lancet       Date:  1979-02-24       Impact factor: 79.321

4.  Plasma-exchange combined with immunosuppressive therapy in myasthenia gravis.

Authors:  P O Behan; R A Shakir; J A Simpson; A K Burnett; T L Allan; G Haase
Journal:  Lancet       Date:  1979-09-01       Impact factor: 79.321

5.  Heterogeneity of acetylcholine receptors in denervated muscle: interactions of receptors with immunoglobulin from patients with myasthenia gravis.

Authors:  T W Mittag; A Tormay; T Massa
Journal:  Mol Pharmacol       Date:  1978-01       Impact factor: 4.436

Review 6.  Myasthenia gravis: a personal view of pathogenesis and mechanism, part 2.

Authors:  J A Simpson
Journal:  Muscle Nerve       Date:  1978 Mar-Apr       Impact factor: 3.217

7.  Antibody to acetylcholine receptor in myasthenia gravis. Prevalence, clinical correlates, and diagnostic value.

Authors:  J M Lindstrom; M E Seybold; V A Lennon; S Whittingham; D D Duane
Journal:  Neurology       Date:  1976-11       Impact factor: 9.910

8.  Antibody to acetylcholine receptor in canine and human myasthenia gravis: differential cross-reactivity with human and rabbit receptor.

Authors:  P C Dau; C S Yano; S J Ettinger
Journal:  Neurology       Date:  1979-07       Impact factor: 9.910

9.  Antibodies from patients with myasthenia gravis recognize determinants unique to extrajunctional acetylcholine receptors.

Authors:  C B Weinberg; Z W Hall
Journal:  Proc Natl Acad Sci U S A       Date:  1979-01       Impact factor: 11.205

10.  An assay for antibodies to human acetylcholine receptor in serum from patients with myasthenia gravis.

Authors:  J Lindstrom
Journal:  Clin Immunol Immunopathol       Date:  1977-01
View more
  1 in total

1.  Myasthenia gravis. Anti-acetylcholine receptor antibodies.

Authors:  D Cerrato; C Ariano; L La Mantia; F Fiacchino; A Sghirlanzoni; A Nespolo; F Corridori; F Cornelio
Journal:  Ital J Neurol Sci       Date:  1981-05
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.