Literature DB >> 7372609

Transsulfuration by human long term lymphoid lines. Normal and cystathionase-deficient cells.

J A Sturman, N G Beratis, L Guarini, G E Gaull.   

Abstract

Long term human lymphoid cells from normal subjects were able to convert [35S]homocysteine to [35S]-cystine. The labeled cystine was found incorporated into proteins. Cells cultured from a patient with vitamin B6-unresponsive cystathioninuria, which contain no measurable cystathionase activity, were unable to perform this conversion. This is the first direct demonstration of transsulfuration by diploid cells in culture.

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Year:  1980        PMID： 7372609

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  4 in total

1.  Differential dependence on cysteine from transsulfuration versus transport during T cell activation.

Authors:  Sanjay K Garg; Zhonghua Yan; Victor Vitvitsky; Ruma Banerjee
Journal:  Antioxid Redox Signal       Date:  2010-12-02       Impact factor: 8.401

Review 2.  Chemical Biology of H2S Signaling through Persulfidation.

Authors:  Milos R Filipovic; Jasmina Zivanovic; Beatriz Alvarez; Ruma Banerjee
Journal:  Chem Rev       Date:  2017-11-07       Impact factor: 60.622

3.  Activated human CD4+ T cells express transporters for both cysteine and cystine.

Authors:  Trine Bøegh Levring; Ann Kathrine Hansen; Bodil Lisbeth Nielsen; Martin Kongsbak; Marina Rode von Essen; Anders Woetmann; Niels Odum; Charlotte Menné Bonefeld; Carsten Geisler
Journal:  Sci Rep       Date:  2012-02-14       Impact factor: 4.379

4.  Transsulfuration Is a Significant Source of Sulfur for Glutathione Production in Human Mammary Epithelial Cells.

Authors:  Andrea D Belalcázar; John G Ball; Leslie M Frost; Monica A Valentovic; John Wilkinson
Journal:  ISRN Biochem       Date:  2014
  4 in total

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