Literature DB >> 737258

Aluminum levels in brain in Alzheimer's disease.

G A Trapp, G D Miner, R L Zimmerman, A R Mastri, L L Heston.   

Abstract

In both human Alzheimer's disease and aluminum encephalopathy of animals, changes are observed in neurofibrillary structures. We have found that brains from Alzheimer patients contain approximately 1.4 times the aluminum level found in a control series. Some possible methodological problems are discussed. We have proposed a plausible chemical mechanism for the changes of aluminum encephalopathy.

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Year:  1978        PMID: 737258

Source DB:  PubMed          Journal:  Biol Psychiatry        ISSN: 0006-3223            Impact factor:   13.382


  15 in total

Review 1.  Human health risk assessment for aluminium, aluminium oxide, and aluminium hydroxide.

Authors:  Daniel Krewski; Robert A Yokel; Evert Nieboer; David Borchelt; Joshua Cohen; Jean Harry; Sam Kacew; Joan Lindsay; Amal M Mahfouz; Virginie Rondeau
Journal:  J Toxicol Environ Health B Crit Rev       Date:  2007       Impact factor: 6.393

2.  Microprobe studies of aluminum accumulation in association with human central nervous system disease.

Authors:  D P Perl; P F Good
Journal:  Environ Geochem Health       Date:  1990-03       Impact factor: 4.609

3.  Aluminum effect on the activity of superoxide dismutase and of other antioxygenic enzymes in vitro.

Authors:  M A Serra; V Barassi; C Canavese; E Sabbioni
Journal:  Biol Trace Elem Res       Date:  1991-10       Impact factor: 3.738

4.  Sequence and functional analysis of the 5'-flanking region of the mouse growth inhibitory factor gene.

Authors:  M Watabe; S Gross; C Lawyer; G J Brewer; T Mashimo; K Watabe
Journal:  Cell Mol Neurobiol       Date:  1997-04       Impact factor: 5.046

5.  Reduced dopamine-beta-hydroxylase activity in Alzheimer's disease.

Authors:  A J Cross; T J Crow; E K Perry; R H Perry; G Blessed; B E Tomlinson
Journal:  Br Med J (Clin Res Ed)       Date:  1981-01-10

6.  Origin and resolution of the aluminum controversy concerning Alzheimer's neurofibrillary degeneration.

Authors:  S S Krishnan; J E Harrison; D R McLachlan
Journal:  Biol Trace Elem Res       Date:  1987-08       Impact factor: 3.738

7.  Applications of neutron activation analysis to the study of age-related neurological diseases.

Authors:  W D Ehmann; W R Markesbery; E J Kasarskis; D E Vance; S S Khare; J D Hord; C M Thompson
Journal:  Biol Trace Elem Res       Date:  1987-08       Impact factor: 3.738

8.  Hippocampal tin, aluminum and zinc in Alzheimer's disease.

Authors:  F M Corrigan; G P Reynolds; N I Ward
Journal:  Biometals       Date:  1993       Impact factor: 2.949

9.  Intranuclear aluminum content in Alzheimer's disease, dialysis encephalopathy, and experimental aluminum encephalopathy.

Authors:  D R Crapper; S Quittkat; S S Krishnan; A J Dalton; U De Boni
Journal:  Acta Neuropathol       Date:  1980       Impact factor: 17.088

10.  Persistent aluminum accumulation after prolonged systemic aluminum exposure.

Authors:  R A Yokel
Journal:  Biol Trace Elem Res       Date:  1983-12       Impact factor: 3.738

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