Literature DB >> 7371801

DOCA administration increases renal phospholipase activity in the rat.

B Baggio, D Bordin, G de Giorgi, S Favaro, A Antonello, A Borsatti.   

Abstract

The phospholipase activity of renal tissue has been evaluated in controls and in DOCA treated rats. DOCA treated animal showed a higher than normal enzyme activity. Since a phospholipase is the key step in prostaglandin biosynthesis, it is suggested that the increased prostaglandin release promoted by mineraloactive steroids is mediated by an activation of this key enzyme.

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Year:  1980        PMID： 7371801     DOI： 10.1007/bf01952330

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  10 in total

1.  Regulation of guanylate and adenylate cyclase activities by lysolecithin.

Authors:  W T Shier; J H Baldwin; M Nilsen-Hamilton; R T Hamilton; N M Thanassi
Journal:  Proc Natl Acad Sci U S A       Date:  1976-05       Impact factor: 11.205

2.  Preliminary studies on a rat kidney phospholipase A2 activating a renin preinhibitor.

Authors:  B Baggio; S Favaro; A Antonello; A Borsatti
Journal:  Res Exp Med (Berl)       Date:  1976-12-30

3.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

4.  Relation between urinary kallikrein and renal function, hypertension, and excretion of sodium and water in man.

Authors:  A Adetuyibi; I H Mills
Journal:  Lancet       Date:  1972-07-29       Impact factor: 79.321

5.  Isolation of a phospholipid renin inhibitor from kidney.

Authors:  S Sen; R R Smeby; F M Bumpus
Journal:  Biochemistry       Date:  1967-06       Impact factor: 3.162

6.  Effects of mineralocorticoids, altered sodium intake, and adrenalectomy on urinary kallikrein in rats.

Authors:  R G Geller; H S Margolius; J J Pisano; H R Keiser
Journal:  Circ Res       Date:  1972-12       Impact factor: 17.367

7.  Release of a prostaglandin E-like substance from canine kidney by bradykinin.

Authors:  J C McGiff; N A Terragno; K U Malik; A J Lonigro
Journal:  Circ Res       Date:  1972-07       Impact factor: 17.367

8.  Significance of phospholipase A for prostaglandin formation.

Authors:  H Kunze; W Vogt
Journal:  Ann N Y Acad Sci       Date:  1971-04-30       Impact factor: 5.691

9.  Interrelations of the renal kallikrein-kinin system and renal prostaglandins in the conscious rat. Influence of mineralocorticoids.

Authors:  A Nasjletti; J C McGiff; J Colina-Chourio
Journal:  Circ Res       Date:  1978-11       Impact factor: 17.367

10.  Possible influence of intrarenal generation of kinins on prostaglandin release from the rabbit perfused kidney.

Authors:  J Colina-Chourio; J C McGiff; M P Miller; A Nasjletti
Journal:  Br J Pharmacol       Date:  1976-10       Impact factor: 8.739
  10 in total

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