Literature DB >> 7371797

Induction of nucleolar segregation in adrenal fasciculata cells by actinomycin D.

M C Magalhães, M M Magalhães.   

Abstract

Actinomycin D administration to young rats provokes segregation of the nucleoli of adrenal fasciculata cells into 5 distinct zones (granular, fibrillar and vacuolar zones, a fibrillar center, and a dense fibrillar or "contrasted" zone); in the cytoplasm, there were dilations of Golgi cisternae. In spite of the nucleolar segregation, the cytoplasmic alterations suggest the maintenance of protein synthesis.

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Year:  1980        PMID： 7371797     DOI： 10.1007/bf01952317

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  9 in total

1.  THE EFFECT OF ACTINOMYCIN D ON THE FINE STRUCTURE OF THE NUCLEOLUS.

Authors:  G I SCHOEFL
Journal:  J Ultrastruct Res       Date:  1964-04

2.  The presence of the adult-type pattern of adrenal steroids in the one day old rat.

Authors:  J E Philpott; M X Zarrow; V H Denenberg
Journal:  Steroids       Date:  1969-07       Impact factor: 2.668

3.  Inhibition of adrenocortical responsiveness to ACTH by actinomycin D in vivo.

Authors:  J Vernikos-Danellis; M Hall
Journal:  Nature       Date:  1965-08-14       Impact factor: 49.962

4.  Sites of protein synthesis in the cells of the zona fasciculata of the young rat adrenal, as shown by electron microscope radioautography.

Authors:  M C Magalhães; M M Magalhães; A Coimbra
Journal:  Am J Anat       Date:  1971-09

5.  Induction of partial nucleolar segregation in hepatic parenchymal cells by actinomycin D following inhibition of ribonucleic acid synthesis by ethionine.

Authors:  P J Goldblatt; R J Sullivan; E Farber
Journal:  Lab Invest       Date:  1969-03       Impact factor: 5.662

6.  Morphologic and metabolic alterations in hepatic cell nucleoli induced by varying doses of actinomycin D.

Authors:  P J Goldblatt; R J Sullivan; E Farber
Journal:  Cancer Res       Date:  1969-01       Impact factor: 12.701

Review 7.  Actinomycin and nucleic acid function.

Authors:  E Reich; I H Goldberg
Journal:  Prog Nucleic Acid Res Mol Biol       Date:  1964

8.  [The phenomenon of nucleolar segregation: specificity of action of certain antimetabolites].

Authors:  R Simard; W Bernhard
Journal:  Int J Cancer       Date:  1966-09-15       Impact factor: 7.396

9.  Actinomycin D: inhibition of phospholipid synthesis in chick embryo cells.

Authors:  I Pastan; R M Friedman
Journal:  Science       Date:  1968-04-19       Impact factor: 47.728
  9 in total

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