Literature DB >> 7371790

Protracted analgesia in young and adult rats maternally exposed to methadone.

I S Zagon, P J McLaughlin.   

Abstract

The analgesic response to the hot-plate test was studied in 21-, 45-, 60-, 120- and 300-day-old rats maternally exposed to methadone (5 mg/kg). An elevation in nociceptive threshold, in the absence of further exposure to methadone, was observed in young and adult rats perinatally subjected to methadone.

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Year:  1980        PMID: 7371790     DOI: 10.1007/bf01952306

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  16 in total

1.  Neonatal addiction: a two-year study. Part I. Clinical and developmental characteristics of infants of mothers on methadone maintenance.

Authors:  C M Ramer; A Lodge
Journal:  Addict Dis       Date:  1975

2.  Methadone assays in pregnant women and progeny.

Authors:  G Blinick; C E Inturrisi; E Jerez; R C Wallach
Journal:  Am J Obstet Gynecol       Date:  1975-03-01       Impact factor: 8.661

3.  The effects of different schedules of methadone treatment on rat brain development.

Authors:  I S Zagon; P J McLaughlin
Journal:  Exp Neurol       Date:  1977-09       Impact factor: 5.330

4.  The distribution of methadone in the nonpregnant, pregnant and fetal rat after acute methadone treatment.

Authors:  M A Peters; M Turnbow; D Buchenauer
Journal:  J Pharmacol Exp Ther       Date:  1972-05       Impact factor: 4.030

5.  Perinatal methadone exposure and brain development: a biochemical study.

Authors:  I S Zagon; P J McLaughlin
Journal:  J Neurochem       Date:  1978-07       Impact factor: 5.372

6.  Effect of chronic maternal methadone exposure on perinatal development.

Authors:  I S Zagon; P J McLaughlin
Journal:  Biol Neonate       Date:  1977

7.  Development of a "blood-brain barrier" to methadone in the newborn rat.

Authors:  M A Peters
Journal:  J Pharmacol Exp Ther       Date:  1975-03       Impact factor: 4.030

8.  Learning ability in adult female rats perinatally exposed to methadone.

Authors:  I S Zagon; P J McLaughlin; C I Thompson
Journal:  Pharmacol Biochem Behav       Date:  1979-06       Impact factor: 3.533

9.  A MEDICAL TREATMENT FOR DIACETYLMORPHINE (HEROIN) ADDICTION. A CLINICAL TRIAL WITH METHADONE HYDROCHLORIDE.

Authors:  V P DOLE; M NYSWANDER
Journal:  JAMA       Date:  1965-08-23       Impact factor: 56.272

10.  Perinatal methadone exposure and its influence on the behavioral ontogeny of rats.

Authors:  I S Zagon; P J McLaughlin
Journal:  Pharmacol Biochem Behav       Date:  1978-11       Impact factor: 3.533

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  2 in total

1.  Neuronal cell deficits following exposure to methadone in rats.

Authors:  I S Zagon; P J McLaughlin
Journal:  Experientia       Date:  1982-10-15

2.  The effects of maternally administered methadone, buprenorphine and naltrexone on offspring: review of human and animal data.

Authors:  W O Farid; S A Dunlop; R J Tait; G K Hulse
Journal:  Curr Neuropharmacol       Date:  2008-06       Impact factor: 7.363

  2 in total

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