Literature DB >> 7371765

Vascular reactivity in hypertension: altered effect of ouabain.

R C Webb, D F Bohr.   

Abstract

Ouabain inhibits the relaxing effect of Ca2+ (but not of Mn2+) on contractile responses in tail artery strips isolated from spontaneously hypertensive and normotensive rats. The magnitude of ouabain inhibition was greater in vascular strips from hypertensive rats suggesting a significant difference in basic membrane function in hypertensive vascular smooth muscle.

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Year:  1980        PMID： 7371765     DOI： 10.1007/bf01953743

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  8 in total

1.  Calcium sequestration by subcellular fractions isolated from vascular smooth muscle: effect of cyclic nucleotides and prostaglandins.

Authors:  R C Webb; R C Bhalla
Journal:  J Mol Cell Cardiol       Date:  1976-02       Impact factor: 5.000

2.  The sodium-potassium adenosine triphosphatase: pharmacological, physiological and biochemical aspects.

Authors:  A Schwartz; G E Lindenmayer; J C Allen
Journal:  Pharmacol Rev       Date:  1975-03       Impact factor: 25.468

3.  Reactivity of vascular smooth muscle in hypertensive rats.

Authors:  E T Holloway; D F Bohr
Journal:  Circ Res       Date:  1973-12       Impact factor: 17.367

4.  Manganese on calcium flux and norepinephrine-induced tension in arterial smooth muscle.

Authors:  J J Keene; C L Seidel; D F Bohr
Journal:  Proc Soc Exp Biol Med       Date:  1972-04

5.  Mechanism of membrane stabilization by calcium in vascular smooth muscle.

Authors:  R C Webb; D F Bohr
Journal:  Am J Physiol       Date:  1978-11

6.  Energy-dependent calcium uptake activity of microsomes from the aorta of normal and hypertensive rats.

Authors:  L Moore; L Hurwitz; G R Davenport; E J Landon
Journal:  Biochim Biophys Acta       Date:  1975-12-16

7.  Hypertension, transmural pressure, and vascular smooth muscle response in rats.

Authors:  T R Hansen; D F Bohr
Journal:  Circ Res       Date:  1975-05       Impact factor: 17.367

Review 8.  Sodium ions, calcium ions, blood pressure regulation, and hypertension: a reassessment and a hypothesis.

Authors:  M P Blaustein
Journal:  Am J Physiol       Date:  1977-05
  8 in total
  3 in total

1.  Effects of ouabain on isolated cerebral and femoral arteries of the cat: a functional and biochemical study.

Authors:  J Marín; C F Sánchez-Ferrer; M Salaices
Journal:  Br J Pharmacol       Date:  1988-01       Impact factor: 8.739

2.  Propranolol induces contractions of canine small and large coronary arteries.

Authors:  P D Turlapaty; B M Altura
Journal:  Basic Res Cardiol       Date:  1982 Jan-Feb       Impact factor: 17.165

3.  Potassium-induced vascular relaxation in two kidney-one clip, renal hypertensive rats.

Authors:  R C Webb; D M Cohen; D F Bohr
Journal:  Pflugers Arch       Date:  1983-01       Impact factor: 3.657
  3 in total

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