Literature DB >> 7371337

A comparison of Tc-99m-labeled human serum albumin and in vitro labeled red blood cells for blood pool studies.

H L Atkins, J F Klopper, A N Ansari, G Meinken, P Richards, S C Srivastava.   

Abstract

A comparison of Tc-99m-labeled human serum albumin (HSA) and in vitro labeled red blood cells (RBC) was carried out in five subjects. The disappearance of radioactivity from the blood was more rapid for HSA (T 1/2, 281.6 minutes, range 202.1--318.3) than for RBC (T 1/2, 1719.8 minutes, range 767.6--5059.5). Urinary excretion was twice as great for HSA. Ratios of activity in heart blood pool to lung and liver were considerably greater for RBC up to 2 hours after administration. The results indicate that labeled RBC are superior to labeled HSA for blood pool imaging.

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Year:  1980        PMID： 7371337     DOI： 10.1097/00003072-198004000-00007

Source DB:  PubMed          Journal:  Clin Nucl Med        ISSN： 0363-9762            Impact factor:   7.794


  6 in total

1.  A new 99mTc-red blood cell labeling procedure for cardiac blood pool imaging: clinical results.

Authors:  H Kelbaek; K Bülow; J Aldershvile; J Møgelvang; S L Nielsen
Journal:  Eur J Nucl Med       Date:  1989

2.  Technetium-99m mercaptoalbumin as a potential substitute or technetium-99m labelled red blood cells.

Authors:  K A Verbeke; H P Vanbilloen; M J De Roo; A M Verbruggen
Journal:  Eur J Nucl Med       Date:  1993-06

3.  First evaluation of technetium-99m dimercaptopropionyl albumin as a possible tracer agent for ventriculography in a volunteer.

Authors:  K A Verbeke; W B Vanhecke; L A Mortelmans; A M Verbruggen
Journal:  Eur J Nucl Med       Date:  1994-09

4.  Atrial natriuretic peptide decreases hepatic and cardiac blood content, but increases intestinal blood content in supine humans.

Authors:  J Peters; D Neuser; W Schaden; J O Arndt
Journal:  Basic Res Cardiol       Date:  1992 May-Jun       Impact factor: 17.165

5.  In vivo/in vitro labeling of red blood cells with 99mTc.

Authors:  R Bauer; I Haluszczynski; H Langhammer; W Bachmann
Journal:  Eur J Nucl Med       Date:  1983

6.  Visualizing cardiac blood pool: comparison of three labeling methods.

Authors:  P Neumann; H Schicha; P Schürnbrand; M Bähre; D Emrich
Journal:  Eur J Nucl Med       Date:  1983
  6 in total

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