Literature DB >> 7370916

The predictive value of serial bone scans in assessing response to chemotherapy in advanced breast cancer.

J D Bitran, C Bekerman, R K Desser.   

Abstract

A retrospective analysis was made of 25 patients with breast cancer treated only with chemotherapy in order to determine the predictive value of technetium-99m bone scanning in determining response to chemotherapy. Whole-body scanning demonstrated bone healing in only 3 of 25 patients. However, the presence of stable disease on bone scan correlated with a good prognosis as 12 patients with stable scans had a significantly longer survival time than did the 13 patients who showed progression on scans (17.7 and 7.8 months, respectively P less than 0.01 greater than 0.005, Wilcoxan). Our analysis indicates that bone scans are a relatively crude technique for monitoring response to chemotherapy in patients with breast cancer.

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Year:  1980        PMID: 7370916     DOI: 10.1002/1097-0142(19800401)45:7<1562::aid-cncr2820450709>3.0.co;2-g

Source DB:  PubMed          Journal:  Cancer        ISSN: 0008-543X            Impact factor:   6.860


  4 in total

1.  Dual-energy CT-scan quantification of recalcification in osteolyses of the vertebral body due to mammary carcinomas in the course of antineoplastic treatment.

Authors:  W Crone-Münzebrock; U M Carl
Journal:  Clin Exp Metastasis       Date:  1990 Mar-Apr       Impact factor: 5.150

2.  The flare phenomenon: far from fair and square.

Authors:  W D van Schelven; E K Pauwels
Journal:  Eur J Nucl Med       Date:  1994-05

3.  Scintigraphic and radiographic patterns of skeletal metastases in breast cancer: value of sequential imaging in predicting outcome.

Authors:  M J Janicek; K Shaffer
Journal:  Skeletal Radiol       Date:  1995-11       Impact factor: 2.199

4.  Markers of type I collagen degradation and synthesis in the monitoring of treatment response in bone metastases from breast carcinoma.

Authors:  C Blomqvist; L Risteli; J Risteli; P Virkkunen; S Sarna; I Elomaa
Journal:  Br J Cancer       Date:  1996-05       Impact factor: 7.640

  4 in total

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