Literature DB >> 7370881

Tumour-associated antigens in lung cancer: the possibility for a serologic assay.

B S Kelly, J G Levy.   

Abstract

Methods were developed to obtain a purified tumour-associated antigen from squamous cell bronchogenic carcinoma of humans. From the preparation a highly specific antitumour antiserum was produced in rabbits. The antiserum was applied to an enzyme-linked immunosorbent assay that subsequently was used as a serologic test for lung cancer. Serum obtained preoperatively from patients with stage I lung cancer was found to be inhibitory in the assay system when compared with serum from healthy individuals.

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Year:  1980        PMID: 7370881      PMCID: PMC1801702     

Source DB:  PubMed          Journal:  Can Med Assoc J        ISSN: 0008-4409            Impact factor:   8.262


  6 in total

1.  Solubilization of an antigen associated with certain bronchial tumours.

Authors:  D Viza; M Louvier; J Phillips; C Boucheix; R A Guerin
Journal:  Eur J Cancer       Date:  1975-11       Impact factor: 9.162

2.  Immunochemical studies on human lung cancer antigens soluble in 50 per cent saturated ammonium sulfate.

Authors:  A Yachi; Y Matsuura; C M Carpenter; L Hyde
Journal:  J Natl Cancer Inst       Date:  1968-04       Impact factor: 13.506

3.  A normal adult and fetal lung antigen present at different quantitative levels in different histologic types of human lung cancer.

Authors:  C E Bell
Journal:  Cancer       Date:  1976-02       Impact factor: 6.860

4.  Alveolar cell carcinoma-like antigen and antibodies in patients with alveolar cell carcinoma and other cancers.

Authors:  A J Mohr; R E Nordquist; E R Rhoades; R E Coalson; J J Coalson
Journal:  Cancer Res       Date:  1974-08       Impact factor: 12.701

5.  Evidence for a common tumour-associated antigen in extracts of human bronchogenic carcinoma.

Authors:  B Kelly; J G Levy
Journal:  Br J Cancer       Date:  1977-06       Impact factor: 7.640

6.  The detection by immunodiffusion of tumour associated antigenic components in extracts of human bronchongenic carcinoma.

Authors:  R D Watson; A G Smith; J G Levy
Journal:  Br J Cancer       Date:  1975-09       Impact factor: 7.640

  6 in total
  1 in total

1.  Specific and nonspecific immunotherapy as an adjunct to curative surgery for cancer of the lung.

Authors:  A C Hollinshead; T H Stewart
Journal:  Yale J Biol Med       Date:  1981 Sep-Oct
  1 in total

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