Literature DB >> 7370170

Phenytoin shortens the half-life of the hypoxic cell radiosensitizer misonidazole in man: implications for possible reduced toxicity.

P Workman, N M Bleehen, C R Wiltshire.   

Abstract

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Year:  1980        PMID： 7370170      PMCID： PMC2010192          DOI： 10.1038/bjc.1980.43

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


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  12 in total

1.  Hypoxic sensitizers: radiobiological studies at the cellular level.

Authors:  E J Hall; L Roizin-Towle
Journal:  Radiology       Date:  1975-11       Impact factor: 11.105

2.  The neurotoxicity of misonidazole and its relationship to dose, half-life and concentration in the serum.

Authors:  M E Saunders; S Dische; P Anderson; I R Flockhart
Journal:  Br J Cancer Suppl       Date:  1978-06

3.  Peripheral neuropathy related to misonidazole: incidence and pathology.

Authors:  R C Urtasun; J D Chapman; M L Feldstein; R P Band; H R Rabin; A F Wilson; B Marynowski; E Starreveld; T Shnitka
Journal:  Br J Cancer Suppl       Date:  1978-06

4.  Radiosensitization by misonidazole (Ro 07-0582). The importance of timing and tumor concentration of sensitizer.

Authors:  N J McNally; J Denekamp; P Sheldon; I R Flockhart; F A Stewart
Journal:  Radiat Res       Date:  1978-03       Impact factor: 2.841

5.  Pharmacological implications of microsomal enzyme induction.

Authors:  A H Conney
Journal:  Pharmacol Rev       Date:  1967-09       Impact factor: 25.468

6.  Liver size and indices of drug metabolism in epileptics.

Authors:  H I Pirttiaho; E A Sotaniemi; J T Ahokas; U Pitkänen
Journal:  Br J Clin Pharmacol       Date:  1978-09       Impact factor: 4.335

7.  Estimation of the hypoxic cell-sensitiser misonidazole and its O-demethylated metabolite in biological materials by reversed-phase high-performance liquid chromatography.

Authors:  P Workman; C J Little; T R Marten; A D Dale; R J Ruane; I R Flockhart; N M Bleehen
Journal:  J Chromatogr       Date:  1978-05-01

8.  The toxicity of the radiosensitizer misonidazole towards hypoxic cells in vitro: a model for mouse and man.

Authors:  I J Stratford; G E Adams
Journal:  Br J Radiol       Date:  1978-09       Impact factor: 3.039

9.  Clinical testing of the radiosensitizer Ro 07-0582: experience with multiple doses.

Authors:  S Dische; M I Saunders; M E Lee; G E Adams; I R Flockhart
Journal:  Br J Cancer       Date:  1977-05       Impact factor: 7.640

10.  Monitoring salivary misonidazole in man: a possible alternative to plasma monitoring.

Authors:  P Workman; C R Wiltshire; P N Plowman; N M Bleehen
Journal:  Br J Cancer       Date:  1978-12       Impact factor: 7.640
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  10 in total

Review 1.  Pharmacokinetic drug interactions with phenytoin (Part II).

Authors:  R L Nation; A M Evans; R W Milne
Journal:  Clin Pharmacokinet       Date:  1990-02       Impact factor: 6.447

2.  No significant effect of metoclopramide on misonidazole elimination in man.

Authors:  K M Williams; E J Begg; D N Wade; K O'Shea
Journal:  Br J Clin Pharmacol       Date:  1983-03       Impact factor: 4.335

3.  No significant effect of cimetidine on the pharmacokinetics of misonidazole in man.

Authors:  E J Begg; K M Williams; D N Wade; K F O'Shea
Journal:  Br J Clin Pharmacol       Date:  1983-05       Impact factor: 4.335

Review 4.  Drug interactions with phenytoin.

Authors:  E Perucca; A Richens
Journal:  Drugs       Date:  1981-02       Impact factor: 9.546

5.  Radiosensitisers.

Authors: 
Journal:  Br Med J       Date:  1980-10-25

Review 6.  Pharmacokinetic interactions with antiepileptic drugs.

Authors:  E Perucca
Journal:  Clin Pharmacokinet       Date:  1982 Jan-Feb       Impact factor: 6.447

7.  Misonidazole neurotoxicity in rats: Part II. Effect of pre- and intermittent treatment with pentobarbital on misonidazole neurotoxicity in the rat.

Authors:  M S Edwards; D G Gordon; A Salamy; V A Levin; T L Phillips
Journal:  J Neurooncol       Date:  1984       Impact factor: 4.130

8.  Phenytoin-induced changes in the pharmacokinetics of misonidazole in radiotherapy patients.

Authors:  J L Moore; I C Paterson; H Newman; S Venables
Journal:  Br J Cancer       Date:  1981-10       Impact factor: 7.640

9.  A comparative investigation of nimorazole and misonidazole as hypoxic radiosensitizers in a C3H mammary carcinoma in vivo.

Authors:  J Overgaard; M Overgaard; O S Nielsen; A K Pedersen; A R Timothy
Journal:  Br J Cancer       Date:  1982-12       Impact factor: 7.640

10.  The role of dexamethasone in the modification of misonidazole pharmacokinetics.

Authors:  D H Jones; N M Bleehen; P Workman; M I Walton
Journal:  Br J Cancer       Date:  1983-10       Impact factor: 7.640
  10 in total

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