Literature DB >> 737005

Marrow aplasia induced by colchicine. A case report.

Y K Liu, R Hymowitz, M G Carroll.   

Abstract

A 70 year old male developed marrow aplasia and pancytopenia after receiving 10 mg of colchicine intravenously over a period of 5 days for acute gouty arthritis. Despite a fatal outcome, evidence of recovery of hematopoiesis was observed in the bone marrow 3 days after the last dose of the drug. The pathogenetic mechanism by which colchicine induced marrow aplasia in this patient remains unclear.

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Year:  1978        PMID: 737005     DOI: 10.1002/art.1780210622

Source DB:  PubMed          Journal:  Arthritis Rheum        ISSN: 0004-3591


  3 in total

Review 1.  Colchicine cardiotoxicity following ingestion of Gloriosa superba tubers.

Authors:  S Mendis
Journal:  Postgrad Med J       Date:  1989-10       Impact factor: 2.401

2.  Colchicine use for familial Mediterranean fever. Observations associated with long-term treatment.

Authors:  R S Peters; T J Lehman; A D Schwabe
Journal:  West J Med       Date:  1983-01

3.  Histopathology of the bone marrow in toxic myelopathy. A study of drug induced lesions in 57 patients.

Authors:  R Krech; J Thiele
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1985
  3 in total

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