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Literature DB >> 7369743

The correlation of disease activity and antibody titers in pemphigus.

Abstract

Twenty cases of pemphigus extracted from the literature and 19 patients from UCLA with pemphigus were studied in detail regarding the possible correlation of pemphigus titer and disease activity. A statistically significant relationship between titer and disease activity, as well as change in titer and change in disease activity, was found. However, in spite of this relationship, serial titers were not found to be consistent enough to be used reliably as a guide to therapy or prognosis in pemphigus.

Entities: Disease Species

Mesh：

Substances：
Autoantibodies

Year: 1980 PMID： 7369743

Source DB: PubMed Journal: Arch Dermatol ISSN： 0003-987X

Keyword Cloud
Cited

11 in total

1. Diagnostic features of pemphigus vulgaris in patients with pemphigus foliaceus: detection of both autoantibodies, long-term follow-up and treatment responses.

Authors: N Sami; K C Bhol; A R Ahmed
Journal: Clin Exp Immunol Date: 2001-09 Impact factor: 4.330

Review 2. Diagnosis and clinical features of pemphigus foliaceus.

Authors: Kirk A James; Donna A Culton; Luis A Diaz
Journal: Dermatol Clin Date: 2011-07 Impact factor: 3.478

3. Nonsecretory IgA1 autoantibodies targeting desmosomal component desmoglein 3 in intraepidermal neutrophilic IgA dermatosis.

Authors: J Wang; J Kwon; X Ding; J A Fairley; D T Woodley; L S Chan
Journal: Am J Pathol Date: 1997-06 Impact factor: 4.307

10. The Usefulness of Indirect Immunofluorescence in Pemphigus and the Natural History of Patients With Initial False-Positive Results: A Retrospective Cohort Study.

Authors: Khalaf Kridin; Reuven Bergman
Journal: Front Med (Lausanne) Date: 2018-10-17

The correlation of disease activity and antibody titers in pemphigus.

1. Diagnostic features of pemphigus vulgaris in patients with pemphigus foliaceus: detection of both autoantibodies, long-term follow-up and treatment responses.

Review 2. Diagnosis and clinical features of pemphigus foliaceus.

3. Nonsecretory IgA1 autoantibodies targeting desmosomal component desmoglein 3 in intraepidermal neutrophilic IgA dermatosis.

Review 4. Antibody-induced proteinase activation: a proposed mechanism for pemphigus.

Review 5. Severity score indexes for blistering diseases.

Review 6. Oral bullous eruption after taking lisinopril--case report and literature review.

7. Pemphigus antibodies identify a cell surface glycoprotein synthesized by human and mouse keratinocytes.

Review 8. Management of autoimmune skin disorders in the elderly.

9. Assessing the autoantibody levels in relation to disease severity and therapy response in pemphigus patients.

10. The Usefulness of Indirect Immunofluorescence in Pemphigus and the Natural History of Patients With Initial False-Positive Results: A Retrospective Cohort Study.