The effect on thromboelastogram of normal blood and procoagulant activity of gel filtered uraemic platelets.

The effect on thromboelastogram of normal blood, and activity of platelet factor 3 of gel filtered uraemic platelets were investigated. It was found that gel filtered uraemic platelets cause shortening of "r" time of thromboelastogram and show increased activity of platelet factor 3 (stypven time). Both phenomena were interpreted as being due to increase of platelet procoagulant activity.