Literature DB >> 7366909

Effect of dihydralazine on the fetus in the treatment of maternal hypertension.

G J Vink, J Moodley, R H Philpott.   

Abstract

The effect on the fetus of lowering the maternal blood pressure with intravenous dihydralazine was studied in 33 patients with diastolic blood pressure of 110 mmHg or more. Nineteen patients showed fetal heart rate (FHR) decelerations coinciding with a fall in blood pressure. Thirteen of the 19 patients had growth-retarded fetuses, while only 1 of 14 patients who showed no FHR changes had a growth-retarded fetus (P greater than .005). Continuous FHR monitoring during the administration of dihydralazine helped identify the compromised fetus if it had been unrecognized at other observations.

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Year:  1980        PMID: 7366909

Source DB:  PubMed          Journal:  Obstet Gynecol        ISSN: 0029-7844            Impact factor:   7.661


  4 in total

Review 1.  Comparative risk-benefit assessment of drugs used in the management of hypertension in pregnancy.

Authors:  P M Kyle; C W Redman
Journal:  Drug Saf       Date:  1992 May-Jun       Impact factor: 5.606

Review 2.  Effects of antihypertensive drugs on the unborn child: what is known, and how should this influence prescribing?

Authors:  S M Khedun; B Maharaj; J Moodley
Journal:  Paediatr Drugs       Date:  2000 Nov-Dec       Impact factor: 3.022

Review 3.  Hypertension in pregnancy. Pathophysiology and management.

Authors:  W F Lubbe
Journal:  Drugs       Date:  1984-08       Impact factor: 9.546

4.  Hydralazine for treatment of severe hypertension in pregnancy: meta-analysis.

Authors:  Laura A Magee; Chris Cham; Elizabeth J Waterman; Arne Ohlsson; Peter von Dadelszen
Journal:  BMJ       Date:  2003-10-25
  4 in total

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