Literature DB >> 7364978

Successful treatment of keratoacanthoma with intralesional fluorouracil.

D K Goette, R B Odom.   

Abstract

Forty-one keratoacanthomas (KA) occurring in thirty patients were treated with weekly intralesional injections of 5-fluorouracil (5-FU). Forty lesions cleared after an average of three injections in an average of 3.4 weeks (range, 2 to 6 weeks). This response suggests that intralesional injections of 5-FU are the treatment of choice for KAs.

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Year:  1980        PMID: 7364978     DOI: 10.1016/s0190-9622(80)80007-7

Source DB:  PubMed          Journal:  J Am Acad Dermatol        ISSN: 0190-9622            Impact factor:   11.527


  4 in total

1.  Giant keratoacanthoma of the upper extremity treated with mohs micrographic surgery: a case report and review of current treatment modalities.

Authors:  Jorge Garcia-Zuazaga; Malcolm Ke; Patrick Lee
Journal:  J Clin Aesthet Dermatol       Date:  2009-08

2.  Antitumor effect of intratumoral administration of fluorouracil/epinephrine injectable gel in C3H mice.

Authors:  N Y Yu; E K Orenberg; E E Luck; D M Brown
Journal:  Cancer Chemother Pharmacol       Date:  1995       Impact factor: 3.333

3.  Evaluation of intralesional 5% 5-fluorouracil in resistant localized plaque psoriasis.

Authors:  Bharat Bhushan Mahajan; Monika Singla
Journal:  Indian Dermatol Online J       Date:  2014-07

4.  Multiple keratoacanthomas developing in healing plaques of Psoriasis.

Authors:  Vineet Relhan; Surabhi Sinha; Nita Khurana; Vijay K Garg
Journal:  Indian Dermatol Online J       Date:  2013-07
  4 in total

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