Cell population kinetics of the germinal centres of lymph nodes of BALB/c mice.

The cell population kinetics of the germinal centres of mesenteric, axillary and inguinal lymph nodes have been studied using 3H-TdR and stathmokinetic techniques. The FLM computed by the Gilbert program showed an ill-defined second peak. The durations of the cell cycle phases were similar in the three anatomical sites. The stathmokinetic data showed only slight variation in the KB and tC(a) values between the different groups of lymph nodes. The Im, IS, and IP values indicated that the number of proliferating cells of the germinal center was very high. When the results obtained with 3H-TdR were compared with those obtained stathmokinetically, good agreement was generally found.