Literature DB >> 7364620

Lung degassing: an evaluation of two methods.

P W Stengel, D G Frazer, K C Weber.   

Abstract

This study compares the effectiveness of the oxygen absorption and vacuum degassing methods for removing trapped gas from lungs. In addition, the effects of changing vacuum pressure, number of times to degas, and lung orientation during the vacuum degassing procedure were evaluated. To evaluate the two methods, a capacitance spirometer was designed and constructed to record lung volume as lungs were vacuum degassed. When lungs containing trapped gas were degassed in a vacuum chamber, they initially expanded, then slightly decreased in volume until the vacuum was released. Lung volume rapidly decreased as the pressure in the vacuum chamber returned to ambient pressure. The results showed that oxygen absorption atelectasis was more effective in removing gas from the lungs than vacuum degassing the lungs. When vacuum degassing was use, it was found to be most effective when the pressure in the chamber was reduced to the vaporization pressure of H2O and when the lungs were degassed twice. Degassing the lungs more than twice did not significantly remove more gas from the lungs. Lung orientation did not affect the removal of gas during vacuum degassing.

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Year:  1980        PMID: 7364620     DOI: 10.1152/jappl.1980.48.2.370

Source DB:  PubMed          Journal:  J Appl Physiol Respir Environ Exerc Physiol        ISSN: 0161-7567


  11 in total

1.  Response to bovine surfactant (surfactant TA) in two different HMD models (lambs and baboons).

Authors:  H Maeta; D Vidyasagar; T Raju; R Bhat; H Matsuda
Journal:  Eur J Pediatr       Date:  1988-02       Impact factor: 3.183

2.  A model of the recruitment-derecruitment and volume of lung units in an excised lung as it is inflated-deflated between minimum and maximum lung volume.

Authors:  D G Frazer; W G Lindsley; W McKinney; J S Reynolds; G N Franz; M Jackson; W T Goldsmith
Journal:  J Biomech Eng       Date:  2013-03-01       Impact factor: 2.097

3.  Automated full-range pressure-volume curves in mice and rats.

Authors:  Annette Robichaud; Liah Fereydoonzad; Nathachit Limjunyawong; Richard Rabold; Benoit Allard; Andrea Benedetti; James G Martin; Wayne Mitzner
Journal:  J Appl Physiol (1985)       Date:  2017-07-27

4.  Lavaged excised rat lungs as a model of surfactant deficiency.

Authors:  M S Bermel; J T McBride; R H Notter
Journal:  Lung       Date:  1984       Impact factor: 2.584

5.  Static mechanics of excised whole lung: theoretical framework and experimental studies.

Authors:  J R Ligas; F P Primiano; G M Saidel
Journal:  Ann Biomed Eng       Date:  1984       Impact factor: 3.934

6.  Measurement of the pressure-volume curve in mouse lungs.

Authors:  Nathachit Limjunyawong; Jonathan Fallica; Maureen R Horton; Wayne Mitzner
Journal:  J Vis Exp       Date:  2015-01-27       Impact factor: 1.355

7.  Morphological mechanism of the development of pulmonary emphysema in klotho mice.

Authors:  Atsuyasu Sato; Toyohiro Hirai; Akihiro Imura; Naoko Kita; Akiko Iwano; Shigeo Muro; Yo-ichi Nabeshima; Bela Suki; Michiaki Mishima
Journal:  Proc Natl Acad Sci U S A       Date:  2007-02-06       Impact factor: 11.205

8.  Comparison of lung sounds and gas trapping in the study of airway mechanics.

Authors:  D G Frazer; L D Smith; L R Brancazio; K C Weber
Journal:  Environ Health Perspect       Date:  1986-04       Impact factor: 9.031

9.  One-session bilateral sequential whole lung lavage (OSBSWLL) for the management of pulmonary alveolar proteinosis.

Authors:  Javier Diaz-Mendoza; Eduardo Celis Valdiviezo; Niral M Patel; Michael J Simoff
Journal:  BMC Pulm Med       Date:  2021-11-09       Impact factor: 3.317

Review 10.  Pulmonary function testing in small laboratory mammals.

Authors:  J J O'Neil; J A Raub
Journal:  Environ Health Perspect       Date:  1984-06       Impact factor: 9.031

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