| Literature DB >> 7364062 |
V Insler, M Glezerman, L Zeidel, D Bernstein, N Misgav.
Abstract
Twenty-five women scheduled for hysterectomy for nonmalignant disease participated in the study. Sperm storage in endocervical crypts was examined in three groups of patients: nine women pretreated with estrogen and inseminated with normal semen, nine women pretreated with gestagen and inseminated with normal semen, and seven women pretreated with estrogen and inseminated with abnormal semen. The number of crypts containing spermatozoa (colonized crypts) and the sperm density per crypt were examined in serially sectioned cervices. In estrogen-pretreated cervices both the percentage of colonized crypts and the sperm density were significantly higher than in gestagen-pretreated cervices. Large and giant crypts proved to be the main storage facility for spermatozoa. The localization of crypts along the endocervical canal did not influence sperm storage. The quality of semen appeared to be of critical importance to sperm storage. The percentage of colonized crypts and sperm density were severly reduced in patients inseminated with abnormal semen.Entities:
Keywords: Artificial Insemination; Biology; Cervical Mucus; Cervix; Clinical Research; Comparative Studies; Contraception; Contraceptive Agents, Estrogen--administraction and dosage; Contraceptive Agents, Female--administraction and dosage; Contraceptive Agents, Progestin--administraction and dosage; Contraceptive Agents--administraction and dosage; Ethinyl Estradiol--administraction and dosage; Evaluation; Family Planning; Genitalia; Genitalia, Female; Germ Cells; In Vitro; Medroxyprogesterone Acetate--administraction and dosage; Mortality; Physiology; Reproduction; Reproductive Technologies; Research Methodology; Sperm Transport; Spermatozoa; Studies; Urogenital System; Uterus
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Year: 1980 PMID： 7364062 DOI： 10.1016/s0015-0282(16)44596-6
Source DB: PubMed Journal: Fertil Steril ISSN： 0015-0282 Impact factor: 7.329