Literature DB >> 7363647

Preliminary clinical experience with dezocine, a new potent analgesic.

W Oosterlinck, A Verbaeys.   

Abstract

The analgesic effect of a single intravenous dose of dezocine at various dosage levels was studied in 41 patients suffering from acute renal colic. Twenty milligrams was found to be a very effective dose. Out of 25 injections an excellent response was recorded on 21 occasions, with a mean duration of effect of 3.5 hours. In a further 3 patients, pain relief was considered as fair and of shorter duration. Pronounced dizziness was a nearly constant side-effect of the drug. There was no overall effect on blood pressure or heart rate.

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Year:  1980        PMID: 7363647     DOI: 10.1185/03007998009109470

Source DB:  PubMed          Journal:  Curr Med Res Opin        ISSN: 0300-7995            Impact factor:   2.580


  2 in total

1.  Pharmacokinetics of dezocine, a new analgesic: effect of dose and route of administration.

Authors:  A Locniskar; D J Greenblatt; M A Zinny
Journal:  Eur J Clin Pharmacol       Date:  1986       Impact factor: 2.953

Review 2.  Dezocine. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy.

Authors:  J J O'Brien; P Benfield
Journal:  Drugs       Date:  1989-08       Impact factor: 9.546

  2 in total

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