Literature DB >> 7362772

Quantitation of glial fibrillary acidic protein in human brain tumours.

S Rasmussen, E Bock, K Warecka, G Althage.   

Abstract

The glial fibrillary acidic protein (GFA) content of 58 human brain tumours was determined by quantitative immunoelectrophoresis, using monospecific antibody against GFA. Astrocytomas, glioblastomas, oligodendrogliomas, spongioblastomas, ependymomas and medulloblastomas contained relatively high amounts of GFA, up to 85 times the concentration in parietal grey substance of normal human brain. GFA was not found in neurinomas, meningiomas, adenomas of the hypophysis, or in a single case of metastasis of adenocarcinoma. Non-glial tumours of craniopharyngioma and haemangioblastoma were infiltrated by reactive astroglia and showed considerable amounts of GFA.

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Year:  1980        PMID： 7362772      PMCID： PMC2010171          DOI： 10.1038/bjc.1980.12

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


  12 in total

1.  Glial fibrillary acidic protein from bovine and rat brain. Degradation in tissues and homogenates.

Authors:  D Dahl
Journal:  Biochim Biophys Acta       Date:  1976-01-20

2.  The role of glial fibrillary acidic protein in the diagnosis of central nervous system tumors.

Authors:  J H Deck; L F Eng; J Bigbee; S M Woodcock
Journal:  Acta Neuropathol       Date:  1978-06-30       Impact factor: 17.088

3.  Astrocyte-specific protein and radial glia in the cerebral cortex of newborn rat.

Authors:  A Bignami; D Dahl
Journal:  Nature       Date:  1974-11-01       Impact factor: 49.962

4.  An acidic protein isolated from fibrous astrocytes.

Authors:  L F Eng; J J Vanderhaeghen; A Bignami; B Gerstl
Journal:  Brain Res       Date:  1971-05-07       Impact factor: 3.252

5.  Immunization, isolation of immunoglobulins, estimation of antibody titre.

Authors:  N Harboe; A Ingild
Journal:  Scand J Immunol Suppl       Date:  1973

6.  Immunochemical and immunofluorescence studies of the glial fibrillary acidic protein in vertebrates.

Authors:  D Dahl; A Bignami
Journal:  Brain Res       Date:  1973-10-26       Impact factor: 3.252

7.  Immunological study of the glial fibrillary acidic protein.

Authors:  C T Uyeda; L F Eng; A Bignami
Journal:  Brain Res       Date:  1972-02-11       Impact factor: 3.252

8.  Determination of glial fibrillary acidic protein (GFAP) in human brain tumors.

Authors:  C M Jacque; C Vinner; M Kujas; M Raoul; J Racadot; N A Baumann
Journal:  J Neurol Sci       Date:  1978-01       Impact factor: 3.181

9.  Ultrastructural localization of glial fibrillary acidic protein in mouse cerebellum by immunoperoxidase labeling.

Authors:  M Schachner; E T Hedley-Whyte; D W Hsu; G Schoonmaker; A Bignami
Journal:  J Cell Biol       Date:  1977-10       Impact factor: 10.539

10.  Antigens in human glioblastomas and meningiomas: Search for tumour and onco-foetal antigens. Estimation of S-100 and GFA protein.

Authors:  L Dittmann; N H Axelsen; B Norgaard-Pedersen; E Bock
Journal:  Br J Cancer       Date:  1977-02       Impact factor: 7.640
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  7 in total

1.  Malignant properties of P635 glioma are independent of glial fibrillary acidic protein expression.

Authors:  A F Chambers; G H Denhardt; S M Wilson; J G Cairncross
Journal:  J Neurooncol       Date:  1991-08       Impact factor: 4.130

Review 2.  Invasiveness of primary brain tumors.

Authors:  O D Laerum; R Bjerkvig; S K Steinsvåg; L de Ridder
Journal:  Cancer Metastasis Rev       Date:  1984       Impact factor: 9.264

3.  Determination of the glial fibrillary acidic protein in human cerebrospinal fluid and in cyst fluid of brain tumors.

Authors:  J Szymaś; S Morkowski; F Tokarz
Journal:  Acta Neurochir (Wien)       Date:  1986       Impact factor: 2.216

4.  Anaplastic human gliomas grown in athymic mice. Morphology and glial fibrillary acidic protein expression.

Authors:  T R Jones; S H Bigner; S C Schold; L F Eng; D D Bigner
Journal:  Am J Pathol       Date:  1981-12       Impact factor: 4.307

5.  Differentiation markers (S-100, GFAP, NSE and D2) in fetal rat brain cells during malignant transformation in cell culture.

Authors:  O D Laerum; S J Mørk; A Haugen; E Bock; L Rosengren; K Haglid
Journal:  J Neurooncol       Date:  1985       Impact factor: 4.130

6.  Glial fibrillary acidic protein (GFAP) in oligodendroglial tumors: gliofibrillary oligodendroglioma and transitional oligoastrocytoma as subtypes of oligodendroglioma.

Authors:  M J Herpers; H Budka
Journal:  Acta Neuropathol       Date:  1984       Impact factor: 17.088

7.  Importance of GFAP isoform-specific analyses in astrocytoma.

Authors:  Emma J van Bodegraven; Jessy V van Asperen; Pierre A J Robe; Elly M Hol
Journal:  Glia       Date:  2019-01-22       Impact factor: 7.452
  7 in total

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