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Literature DB >> 7361257

Experimentally induced cerebral aneurysms in rats: Part V. Relation of hemodynamics in the circle of Willis to formation of aneurysms.

N Hashimoto, H Handa, I Nagata, F Hazama.

Abstract

All the rats were made hypertensive and fed beta-aminopropionitrile. Among them, cerebral aneurysms were never found in rats without carotid ligation. In rats with ligation of one or both common carotid arteries, cerebral aneurysms developed on the vessels where hemodynamic stresses were apparently increased. The relationship of hemodynamics in the circle of Willis to the development of cerebral aneurysms is discussed, being compared with findings in spontaneous lesions in man.

Entities: Chemical Disease Species

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Year: 1980 PMID： 7361257

Source DB: PubMed Journal: Surg Neurol ISSN： 0090-3019

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Cited

41 in total

1. Experimental cerebral aneurysms in the female heterozygous Blotchy mouse.

Authors: M Coutard
Journal: Int J Exp Pathol Date: 1999-12 Impact factor: 1.925

2. PGE(2) -EP(2) signalling in endothelium is activated by haemodynamic stress and induces cerebral aneurysm through an amplifying loop via NF-κB.

Authors: T Aoki; M Nishimura; T Matsuoka; K Yamamoto; T Furuyashiki; H Kataoka; S Kitaoka; R Ishibashi; A Ishibazawa; S Miyamoto; R Morishita; J Ando; N Hashimoto; K Nozaki; S Narumiya
Journal: Br J Pharmacol Date: 2011-07 Impact factor: 8.739

10. Complex hemodynamics at the apex of an arterial bifurcation induces vascular remodeling resembling cerebral aneurysm initiation.

Authors: Hui Meng; Zhijie Wang; Yiemeng Hoi; Ling Gao; Eleni Metaxa; Daniel D Swartz; John Kolega
Journal: Stroke Date: 2007-05-10 Impact factor: 7.914

Experimentally induced cerebral aneurysms in rats: Part V. Relation of hemodynamics in the circle of Willis to formation of aneurysms.

1. Experimental cerebral aneurysms in the female heterozygous Blotchy mouse.

2. PGE(2) -EP(2) signalling in endothelium is activated by haemodynamic stress and induces cerebral aneurysm through an amplifying loop via NF-κB.

Review 3. Intracranial aneurysms: links among inflammation, hemodynamics and vascular remodeling.

4. In vivo study of flow pattern at human carotid bifurcation with regard to aneurysm development.

Review 5. High wall shear stress and spatial gradients in vascular pathology: a review.

6. Nascent aneurysm formation at the basilar terminus induced by hemodynamics.

7. Lack of aneurysm formation after carotid artery ligation in rabbits: a polymer MICROFIL® study.

8. Hemodynamics of Cerebral Aneurysms.

9. Hemodynamic stress in terminal saccular aneurysms: a laser-Doppler study.

10. Complex hemodynamics at the apex of an arterial bifurcation induces vascular remodeling resembling cerebral aneurysm initiation.