Literature DB >> 7359521

Pyrido[2,1-b]quinazolinecarboxylic acids as orally active antiallergy agents.

J W Tilley, R A LeMahieu, M Carson, R W Kierstead, H W Baruth, B Yaremko.   

Abstract

A series of 8-substituted pyrido[2,1-]quinazoline-2-carboxylic acids was prepared by the nickel carbonyl mediated carboxylation of the corresponding bromides. The activities of these compounds in the rat PCA test are comparable to those of the corresponding 2-substituted pyrido[2,1-b]quinazoline-8-carboxylic acids.

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Year:  1980        PMID: 7359521     DOI: 10.1021/jm00175a020

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


  1 in total

1.  Ro 21-7634, a new antiallergic agent with potent oral activity.

Authors:  R A Salvador; L B Czyzewski; H Baruth; A Hooper; A Medford; D Miller; T van Trabert; B Yaremko; A F Welton
Journal:  Agents Actions       Date:  1981-07
  1 in total

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