Literature DB >> 7358147

Human neuropharmacological findings with oxapadol (MD 720111), a new non-narcotic analgesic.

F Boureau, B Laquais, M Vadrot, J C Willer.   

Abstract

The effects of oxapadol, a new non-narcotic analgesic, were tested in man using the electrically-induced nociceptive flexion reflex in the flexor muscles of the lower limb as an index of pain. The drug caused a significant increase in the threshold of the reflex whereas no change was noted with placebo.

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Year:  1980        PMID： 7358147     DOI： 10.1007/bf02003997

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  6 in total

1.  Determination of an indiction of pain by the sapheno-bicipital reflex method: physiological and pharmacological variations.

Authors:  J C Willer; N Bathien
Journal:  Electromyogr Clin Neurophysiol       Date:  1975 Apr-Jun

2.  [The influence of anticipation of pain on heart and respiratory rates and on the pain reflex in man].

Authors:  J C Willer
Journal:  Physiol Behav       Date:  1975-10

3.  Comparative study of perceived pain and nociceptive flexion reflex in man.

Authors:  Jean Clau de Willer
Journal:  Pain       Date:  1977-02       Impact factor: 6.961

4.  Pharmacological modulations on the nociceptive flexion reflex in man.

Authors:  J C Willer; N Bathien
Journal:  Pain       Date:  1977-04       Impact factor: 6.961

5.  The analysis of the two-period repeated measurements crossover design with application to clinical trials.

Authors:  S Wallenstein; A C Fisher
Journal:  Biometrics       Date:  1977-03       Impact factor: 2.571

6.  Study of naloxone in normal awake man: effects on spinal reflexes.

Authors:  F Boureau; J C Willer; C Dauthier
Journal:  Neuropharmacology       Date:  1978-08       Impact factor: 5.250
  6 in total

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