Literature DB >> 7358127

Involvement of ribonuclease in the interactions of macrophages and fibroblasts in experimental silicosis.

S Aho, E Kulonen.   

Abstract

Decreased ribonuclease activity in the supernatant from silica-treated macrophages is associated with the enhanced protein synthesis in granulation-tissue slices incubated in this supernatant, and with the decreased degradation of polysomes in granuloma slices and of polysomes isolated from the granulation tissue. The phagocytized silica particles adsorb ribonuclease and perhaps other proteins and thus remove them from the macrophage supernatant.

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Year:  1980        PMID： 7358127     DOI： 10.1007/bf02003951

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  12 in total

1.  Correlation of tensile strength and chemical composition in experimental granuloma.

Authors:  J VILJANTO; E KULONEN
Journal:  Acta Pathol Microbiol Scand       Date:  1962

2.  The effect of silica-treated macrophages on the synthesis of collagen and other proteins in vitro.

Authors:  M Aalto; M Potila; E Kulonen
Journal:  Exp Cell Res       Date:  1976-01       Impact factor: 3.905

3.  Effect of silica-liberated macrophage factors on protein synthesis in cell-free systems.

Authors:  S Aho; E Kulonen
Journal:  Exp Cell Res       Date:  1977-01       Impact factor: 3.905

4.  Protein adsorption to monosodium urate, calcium pyrophosphate dihydrate, and silica crystals: relationship to the pathogenesis of crystal-induced inflammation.

Authors:  F Kozin; D J McCarty
Journal:  Arthritis Rheum       Date:  1976 May-Jun

5.  Activity of a macrophage factor in collagen formation by silica.

Authors:  A G Heppleston; J A Styles
Journal:  Nature       Date:  1967-04-29       Impact factor: 49.962

6.  Physico-chemical properties of silica in relation to its toxicity.

Authors:  T Nash; A C Allison; J S Harington
Journal:  Nature       Date:  1966-04-16       Impact factor: 49.962

7.  Amino acid metabolism of experimental granulation tissue in vitro.

Authors:  M Aalto; K Lampiaho; J Pikkarainen; E Kulonen
Journal:  Biochem J       Date:  1973-04       Impact factor: 3.857

8.  Magnesium precipitation of ribonucleoprotein complexes. Expedient techniques for the isolation of undergraded polysomes and messenger ribonucleic acid.

Authors:  R D Palmiter
Journal:  Biochemistry       Date:  1974-08-13       Impact factor: 3.162

9.  Alkaline ribonuclease associated with polyribosomes in fibroblasts of experimental granulation tissue.

Authors:  M T Jalkanen; S Aho; E Kulonen
Journal:  Acta Chem Scand B       Date:  1978

10.  Alkaline ribonuclease and ribonuclease inhibitor in mammary gland during the lactation cycle and in the R3230AC mammary tumour.

Authors:  D K Liu; G H Williams; P J Fritz
Journal:  Biochem J       Date:  1975-04       Impact factor: 3.857
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  3 in total

1.  A further experimental study of the antisilicotic effect of glutamate.

Authors:  K I Morosova; B A Katsnelson; G V Belobragina
Journal:  Br J Ind Med       Date:  1984-11

2.  Isolation of silica-dependent protein from rat lung with special reference to development of fibrosis.

Authors:  M Aalto; E Kulonen; J Pikkarainen
Journal:  Br J Exp Pathol       Date:  1989-04

3.  On the defensive action of glutamate against the cytotoxicity and fibrogenicity of quartz dust.

Authors:  K I Morosova; G V Aronova; B A Katsnelson; B T Velichkovski; A M Genkin; L N Elnichnykh; L I Privalova
Journal:  Br J Ind Med       Date:  1982-08
  3 in total

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