Literature DB >> 7358109

Effect of some nitrotoluenes on the biotransformation of xenobiotics in rats.

R D Short, C C Lee.   

Abstract

Male rats were treated with phenobarbital, a dinitrotoluene (2,4-DNT or 2,6-DNT), or 2,4,6-trinitrotoluene (2,4,6-TNT); and the biotransformation of model xenobiotics was determined. Phenobarbital produced a stimulation, and 2,6-DNT produced a biphasic effect in biotransformation.

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Year:  1980        PMID: 7358109     DOI: 10.1007/bf02003999

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  2 in total

1.  FURTHER STUDIES ON THE INHIBITION AND STIMULATION OF MICROSOMAL DRUG METABOLIZING ENZYMES OF RAT LIVER BY VARIOUS COMPOUNDS.

Authors:  R KATO; E CHIESARA; P VASSANELLI
Journal:  Biochem Pharmacol       Date:  1964-01       Impact factor: 5.858

2.  The stimulation and inhibition of hepatic microsomal drug-metabolizing enzymes with special reference to effects of environmental contaminants.

Authors:  J R Fouts
Journal:  Toxicol Appl Pharmacol       Date:  1970-11       Impact factor: 4.219

  2 in total

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