Literature DB >> 7357680

Cadmium-induced reduction of bone alkaline phosphatase and its prevention by zinc.

F W Bonner, L J King, D V Parke.   

Abstract

The dietary exposure of rats to cadmium (75 ppm) for periods of up to 48 weeks caused an accumulation of cadmium in the femur, and an inhibition of the accumulation of zinc in the bone. After 48 weeks of cadmium treatment, there was a decreased activity of alkaline phosphatase in the femur. This effect was prevented by a simultaneous dietary supplement of zinc (300 ppm).

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Year:  1980        PMID： 7357680     DOI： 10.1016/0009-2797(80)90155-6

Source DB:  PubMed          Journal:  Chem Biol Interact        ISSN： 0009-2797            Impact factor:   5.192


  3 in total

1.  Mobilization of tissue cadmium in mice and calves and reversal of cadmium induced tissue damage in calves by zinc.

Authors:  C S Reddy; F K Mohammad; V K Ganjam; M A Martino; E M Brown
Journal:  Bull Environ Contam Toxicol       Date:  1987-08       Impact factor: 2.151

2.  Increased zinc accumulation in mineralized osteosarcoma tissue measured by confocal synchrotron radiation micro X-ray fluorescence analysis.

Authors:  Mirjam Rauwolf; Bernhard Pemmer; Andreas Roschger; Anna Turyanskaya; Stephan Smolek; Angelika Maderitsch; Peter Hischenhuber; Martin Foelser; Rolf Simon; Susanna Lang; Stephan E Puchner; Reinhard Windhager; Klaus Klaushofer; Peter Wobrauschek; Jochen G Hofstaetter; Paul Roschger; Christina Streli
Journal:  Xray Spectrom       Date:  2016-12-21       Impact factor: 1.488

3.  Spatial distribution of the trace elements zinc, strontium and lead in human bone tissue.

Authors:  B Pemmer; A Roschger; A Wastl; J G Hofstaetter; P Wobrauschek; R Simon; H W Thaler; P Roschger; K Klaushofer; C Streli
Journal:  Bone       Date:  2013-08-09       Impact factor: 4.398
  3 in total

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