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Literature DB >> 7354837

Structure of the junction between communicating cells.

Abstract

An 18-A resolution map of the 'gap junction' has been obtained by electron microscopy. The protein oligomer in the junctional membranes, the 'connexon', is a cyclinder composed of six subunits which are titled around its axis. Analysis of two different subunit configurations suggests how the connexon might regulate the passage of small molecules between cell interiors.

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Year: 1980 PMID： 7354837 DOI： 10.1038/283545a0

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

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Cited

163 in total

1. Inhibition of single Shaker K channels by kappa-conotoxin-PVIIA.

Authors: David Naranjo
Journal: Biophys J Date: 2002-06 Impact factor: 4.033

2. Conformational changes in surface structures of isolated connexin 26 gap junctions.

Authors: Daniel J Müller; Galen M Hand; Andreas Engel; Gina E Sosinsky
Journal: EMBO J Date: 2002-07-15 Impact factor: 11.598

3. Membrane modifications in the course of hepatocyte isolation.

Authors: E Falcieri; R Del Coco; A R Mariani; P Gobbi; P Santi
Journal: Cytotechnology Date: 1990-11 Impact factor: 2.058

4. Tetracycline-regulated expression enables purification and functional analysis of recombinant connexin channels from mammalian cells.

Authors: Irina V Koreen; Wafaa A Elsayed; Yu J Liu; Andrew L Harris
Journal: Biochem J Date: 2004-10-01 Impact factor: 3.857

10. Quantitative gap junction alterations in mammalian heart cells quickly frozen or chemically fixed after electrical uncoupling.

Authors: J Délèze; J C Hervé
Journal: J Membr Biol Date: 1986 Impact factor: 1.843

Structure of the junction between communicating cells.

1. Inhibition of single Shaker K channels by kappa-conotoxin-PVIIA.

2. Conformational changes in surface structures of isolated connexin 26 gap junctions.

3. Membrane modifications in the course of hepatocyte isolation.

4. Tetracycline-regulated expression enables purification and functional analysis of recombinant connexin channels from mammalian cells.

5. Modelling butterfly wing eyespot patterns.

Review 6. Structural basis for the selective permeability of channels made of communicating junction proteins.

Review 7. Voltage-dependent conformational changes in connexin channels.

Review 8. Structure of the gap junction channel and its implications for its biological functions.

9. Autoregulation of connexin43 gap junction formation by internally translated isoforms.

10. Quantitative gap junction alterations in mammalian heart cells quickly frozen or chemically fixed after electrical uncoupling.