Leptospirosis in lambs.

Two major episodes of acute hemolytic disease in lambs were associated with high mortality. Clinical signs were severe depression, dyspnea, and tachycardia. Gross postmortem findings included hemoglobinuria and icterus. Histologic examination revealed tubular necrosis and periacinar hepatocellular necrosis. Leptospira interrogans serotype pomona was proposed as the causative agent because high serum antibody titers for this bacterium were found in lambs and ewes in the affected flocks.