Literature DB >> 7353425

Pentazocine abuse. Report of a case with pulmonary arterial cellulose granulomas and pulmonary hypertension.

R J Houck, G L Bailey, P J Daroca, F Brazda, F B Johnson, R C Klein.   

Abstract

We report a patient who developed pulmonary hypertension following repeated intravenous injection of dissolved pentazocine tablets. Through analysis of lung biopsy material, this was shown to be due to embolization of the cellulose filler in the tablet and the tissue reaction it produced. Administration of prednisone appeared to improve the patient's clinical state.

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Year:  1980        PMID： 7353425     DOI： 10.1378/chest.77.2.227

Source DB:  PubMed          Journal:  Chest        ISSN： 0012-3692            Impact factor:   9.410


  2 in total

Review 1.  Pulmonary complications of intravenous drug misuse. 1. Epidemiology and non-infective complications.

Authors:  C R Hind
Journal:  Thorax       Date:  1990-11       Impact factor: 9.139

2.  Unusual pulmonary vascular lesions after intravenous injections of microcrystalline cellulose. A complication of pentazocine tablet abuse.

Authors:  T B Zeltner; U Nussbaumer; O Rudin; A Zimmermann
Journal:  Virchows Arch A Pathol Anat Histol       Date:  1982
  2 in total

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