| Literature DB >> 7353373 |
L R Baker, J W Muir, W R Cattell, K A Tucker, V L Sharman, F J Goodwin, F P Marsh, W Hately, A G Morgan, D M de Saintonge.
Abstract
Hypercalcaemia regularly occurs when "prophylactic" 1,25-dihydroxyvitamin D3 (1,25[OH)2D3) in a dose of 1.0 microgram daily is given to haemodialysis patients without clinical biochemical or radiological evidence of osteodystophy. This dose is too large for such patients. Hypercalcaemia may persist for several weeks after withdrawal of 1,25(OH)2D3, particularly when previous attempts at control by dosage reduction have failed. Hypercalcaemia is better managed by stopping 1,25(OH)2D3, albeit temporarily, than by reducing the dose.Entities:
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Year: 1980 PMID： 7353373 DOI： 10.1159/000403282
Source DB: PubMed Journal: Contrib Nephrol ISSN： 0302-5144 Impact factor: 1.580