| Literature DB >> 7353229 |
K K Park, M C Archer, J S Wishnok.
Abstract
Administration of N-nitrosodi-n-propylamine to rats leads to the formation of 7-n-propylguanine but not 7-isopropylguanine in hepatic DNA. For RNA, a small amount of the rearranged adduct is formed. Alkylation of DNA and RNA therefore appears to occur primarily via a bimolecular reaction rather than a unimolecular pathway involving free alkyl cations.Entities:
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Year: 1980 PMID： 7353229 DOI： 10.1016/0009-2797(80)90028-9
Source DB: PubMed Journal: Chem Biol Interact ISSN： 0009-2797 Impact factor: 5.192