| Literature DB >> 7350655 |
F A Fuhrman, G J Fuhrman, Y H Kim, L A Pavelka, H S Mosher.
Abstract
A new N-methylpurine riboside (doridosine), probably N1-Methylisoguanosine, was isolated from the digestive glands of a nudibranch. Doridosine produces prolonged hypotension and bradycardia in anesthetized rats, decreases the rate and the amplitude of contraction of guinea pig atria in vitro, and causes the heart rate in anesthetized mice to be reduced by 50 percent for many hours after which the animals recover completely.Entities:
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Year: 1980 PMID： 7350655 DOI： 10.1126/science.7350655
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728