Literature DB >> 7350279

Cerebrospinal fluid antibiotic levels during treatment of shunt infections.

S L Wald, R L McLaurin.   

Abstract

Twenty patients with documented cerebrospinal fluid shunt infections were treated with daily intraventricular injections of methicillin, cephalothin, or gentamicin without removal of the shunt or external ventricular drainage. Periodic determinations of intraventricular antibiotic concentration revealed significant levels in relation to the established minimum inhibitory concentration in all cases.

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Year:  1980        PMID: 7350279     DOI: 10.3171/jns.1980.52.1.0041

Source DB:  PubMed          Journal:  J Neurosurg        ISSN: 0022-3085            Impact factor:   5.115


  16 in total

Review 1.  Pharmacokinetics and pharmacodynamics of cephalosporins in cerebrospinal fluid.

Authors:  I Lutsar; I R Friedland
Journal:  Clin Pharmacokinet       Date:  2000-11       Impact factor: 6.447

2.  Prevention of hydrocephalus shunt catheter colonisation in vitro by impregnation with antimicrobials.

Authors:  R Bayston; N Grove; J Siegel; D Lawellin; S Barsham
Journal:  J Neurol Neurosurg Psychiatry       Date:  1989-05       Impact factor: 10.154

3.  Cerebrospinal fluid shunting for hydrocephalus: a retrospective analysis.

Authors:  J D Metzemaekers; J W Beks; J S van Popta
Journal:  Acta Neurochir (Wien)       Date:  1987       Impact factor: 2.216

4.  Intraventricular vancomycin in the treatment of ventriculitis associated with cerebrospinal fluid shunting and drainage.

Authors:  R Bayston; C A Hart; M Barnicoat
Journal:  J Neurol Neurosurg Psychiatry       Date:  1987-11       Impact factor: 10.154

Review 5.  Clinical pharmacokinetics of cerebrospinal fluid.

Authors:  M Bonati; J Kanto; G Tognoni
Journal:  Clin Pharmacokinet       Date:  1982 Jul-Aug       Impact factor: 6.447

6.  The management of cerebrospinal fluid shunt infections: a clinical experience.

Authors:  H E James; J W Walsh; H D Wilson; J D Connor
Journal:  Acta Neurochir (Wien)       Date:  1981       Impact factor: 2.216

7.  Shunt malfunction in relation to shunt infection.

Authors:  V Vanaclocha; N Sáiz-Sapena; J Leiva
Journal:  Acta Neurochir (Wien)       Date:  1996       Impact factor: 2.216

8.  Staphylococcus aureus ventriculitis treated with single-dose intraventricular vancomycin or daptomycin (LY146032): bacterial and antibiotic kinetics in hydrocephalic rabbits.

Authors:  C S Haworth; M W Sobieski; W M Scheld; T S Park
Journal:  Antimicrob Agents Chemother       Date:  1990-02       Impact factor: 5.191

9.  Haemophilus influenzae meningitis in the presence of cerebrospinal fluid shunts.

Authors:  S Stern; R Bayston; R J Hayward
Journal:  Childs Nerv Syst       Date:  1988-06       Impact factor: 1.475

Review 10.  Antibiotic Distribution into Cerebrospinal Fluid: Can Dosing Safely Account for Drug and Disease Factors in the Treatment of Ventriculostomy-Associated Infections?

Authors:  Nilesh Kumta; Jason A Roberts; Jeffrey Lipman; Menino Osbert Cotta
Journal:  Clin Pharmacokinet       Date:  2018-04       Impact factor: 6.447

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