Literature DB >> 7347232

[Combined action of remantadine (amantadine) and ribavirin on experimental influenza].

G A Galegov, V Knight, N L Pushkarskaia, S Z Wilson, R B Couch.   

Abstract

The inhibiting effect of remantadine (amantadine) and ribavirin combination on experimental influenza infection was studied in comparison of the effect of each of these drugs alone. The combination of the two chemopreparations was found to inhibit synthesis of influenza A virus proteins in cell culture more effectively, to ensure maximum survival rate of white mice treated with these preparations by oral, aerosol and intraperitoneal routes of administration.

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Year:  1981        PMID: 7347232

Source DB:  PubMed          Journal:  Vopr Virusol        ISSN: 0507-4088


  1 in total

1.  The combination of ribavirin and ozeltamivir effectively inhibits reproduction of influenza A virus resistant to rimantadine (amantadine) in vitro and in vivo.

Authors:  P G Deryabin; G A Galegov; I D Konstantinova; I S Muzyka; A I Miroshnikov; D K L'vov
Journal:  Dokl Biochem Biophys       Date:  2014-05-03       Impact factor: 0.788

  1 in total

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