Literature DB >> 7346148

Potentials and limitations of a clonogenic cell assay for human brain tumors.

M L Rosenblum, D V Dougherty, D F Deen, C B Wilson.   

Abstract

Single cells from biopsies of ten malignant gliomas were treated with 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU) in vitro, and tumor cell survival was compared to patient response to nitrosourea therapy. The limitations of the methods and their interpretations and future prospects for clonogenic cell analyses are discussed.

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Year:  1981        PMID： 7346148

Source DB:  PubMed          Journal:  Cancer Treat Rep        ISSN： 0361-5960


  4 in total

1.  Time-schedule dependency of the inhibiting activity of various anticancer drugs in the clonogenic assay.

Authors:  Y Matsushima; F Kanzawa; A Hoshi; E Shimizu; H Nomori; Y Sasaki; N Saijo
Journal:  Cancer Chemother Pharmacol       Date:  1985       Impact factor: 3.333

2.  The effect of DFMO induced uptake of [3H] putrescine on human glioma cells.

Authors:  E S Redgate; D Alexander; T R Magra; J S Henretty; K D Patrene; S S Boggs
Journal:  J Neurooncol       Date:  2001-11       Impact factor: 4.130

3.  In vitro chemosensitivity of brain tumors to cisplatin and its analogues, iproplatin and carboplatin.

Authors:  P Dodion; C Sanders; P Georges; Y Kenis
Journal:  Cancer Chemother Pharmacol       Date:  1988       Impact factor: 3.333

4.  New sensitivity test using flow cytometry.

Authors:  K Kawamoto; K Kawakami; Y Kawamura; H Matsumura; A Ohyama
Journal:  J Neurooncol       Date:  1988-12       Impact factor: 4.130
  4 in total

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