Literature DB >> 7345725

The effect of chronic neonatal guanethidine treatment on body composition in pigs.

N G Gregory, D Lister, R D Lovell.   

Abstract

The effect of neonatal guanethidine administration (30 mg/kg/day) during the first 32 days of life on body composition at 20 weeks of age, was assessed in two breeds of pig which were known to differ in their sympathetic responsiveness. Guanethidine administration increased the proportion of fat and decreased the proportion and absolute weight of lean in the Pietrain breed; and it had no effect in Gloucester Old Spots. Thus it can be inferred that endogenous noradrenaline is responsible for promoting leanness in a pig breed with known sympathetic overactivity.

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Year:  1981        PMID： 7345725     DOI： 10.1007/bf02214983

Source DB:  PubMed          Journal:  Vet Res Commun        ISSN： 0165-7380            Impact factor:   2.459


  11 in total

1.  Chronic guanethidine and adrenal medullary function in the rat.

Authors:  W M Romanyshyn; D E Clarke
Journal:  J Pharm Pharmacol       Date:  1976-10       Impact factor: 3.765

Review 2.  Role of brain monoamines and histamine in regulation of anterior pituitary secretion.

Authors:  R I Weiner; W F Ganong
Journal:  Physiol Rev       Date:  1978-10       Impact factor: 37.312

3.  Fat mobilization in Pietrain and Large White pigs.

Authors:  J D Wood; N G Gregory; G M Hall; D Lister
Journal:  Br J Nutr       Date:  1977-03       Impact factor: 3.718

4.  Effects of chronic guanethidine treatment and adrenal medullectomy on plasma levels of catecholamines and corticosterone in forcibly immobilized rats.

Authors:  R Kvetnansky; V K Weise; N B Thoa; I J Kopin
Journal:  J Pharmacol Exp Ther       Date:  1979-05       Impact factor: 4.030

5.  A differential effect of chronically administered guanethidine on sympathetic neurotransmission to the dog heart and mesenteric arterial blood vessels.

Authors:  D E Clarke; B S Jandhyala; I Cavero; B N Dixit; J P Buckley
Journal:  Can J Physiol Pharmacol       Date:  1974-06       Impact factor: 2.273

6.  A new method of destroying adrenergic nerves in adult animals using guanethidine.

Authors:  G Burnstock; B Evans; B J Gannon; J W Heath; V James
Journal:  Br J Pharmacol       Date:  1971-10       Impact factor: 8.739

7.  Fat mobilisation in large white pigs selected for low backfat thickness.

Authors:  N G Gregory; J D Wood; M Enser; W C Smith; M Ellis
Journal:  J Sci Food Agric       Date:  1980-06       Impact factor: 3.638

8.  Autonomic responsiveness in stress-sensitive and stress-resistant pigs.

Authors:  N G Gregory; D Lister
Journal:  J Vet Pharmacol Ther       Date:  1981-03       Impact factor: 1.786

9.  Regional changes in brain catecholamine content following administration of guanethidine to neonatal rats.

Authors:  Y Nomura; F Naitoh; T Segawa
Journal:  Jpn J Pharmacol       Date:  1975-12

10.  Autonomic and non-autonomic control of cardiovascular function in stress-sensitive pigs.

Authors:  N G Gregory; S B Wotton
Journal:  J Vet Pharmacol Ther       Date:  1981-09       Impact factor: 1.786
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