| Literature DB >> 7344104 |
D Castelino, A Saul, P Myler, C Kidson, H Thomas, R Cooke.
Abstract
Analysis of ovalocytosis in families has demonstrated dominant inheritance. This conclusion is based on finding ovalocytic children of ovalocytic Melanesian mothers and normocytic Caucasian fathers. Inheritance of resistance to thermal deformation and to crenation upon storage correlated with inheritance of ovalocytic erythrocyte morphology. The latter was associated with in vitro resistance to invasion by P. falciparum.Entities:
Mesh:
Year: 1981 PMID: 7344104
Source DB: PubMed Journal: Southeast Asian J Trop Med Public Health ISSN: 0125-1562 Impact factor: 0.267