Literature DB >> 7341542

Circulating platelet aggregates: a chronic platelet activation in patients with transient ischaemic attacks.

M De Marinis, C Fieschi, M Prencipe, R Falchetti, S Paolucci.   

Abstract

Platelet hyperaggregability was tested in 62 TIA patients by means of the formalin fixing principle of Wu and Hoak. Compared to age-matched controls, the platelet aggregates ratio (PAR) was reduced from 0.99 +/- 0.04 SD to 0.807 +/- 0.14 SD. This means a highly significant increase of circulating platelet aggregates (CPA) in untreated TIA patients, regardless of the interval sinche the last attack (from 2 days to 1 year). PAR was especially reduced in patients with abnormal angiography (expressing pronounced cerebral or diffuse ATS) and it was possibly affected by previous antiplatelet treatment with ASA.

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Year:  1980        PMID： 7341542     DOI： 10.1007/bf02335846

Source DB:  PubMed          Journal:  Ital J Neurol Sci        ISSN： 0392-0461


  25 in total

1.  Methods for detection of hypersensitive platelets. Philadelphia, June 1977.

Authors:  M A Packham
Journal:  Thromb Haemost       Date:  1978-08-31       Impact factor: 5.249

2.  Summary of the International Round Table Conferece on platelet aggregation in the pathogenesis of cerebrovascular disorders.

Authors:  J S Meyer
Journal:  Stroke       Date:  1975 May-Jun       Impact factor: 7.914

3.  MURAL THROMBOSIS OF THE INTERNAL CAROTID ARTERY AND SUBSEQUENT EMBOLISM.

Authors:  A J GUNNING; G W PICKERING; A H ROBB-SMITH; R R RUSSELL
Journal:  Q J Med       Date:  1964-01

4.  Observations on the retinal blood-vessels in monocular blindness.

Authors:  R W RUSSELL
Journal:  Lancet       Date:  1961-12-30       Impact factor: 79.321

5.  Platelet adhesiveness, plasma fibrinogen, and fibrinolytic activity in young patients with ischaemic stroke.

Authors:  S C Sharma; G P Vijayan; H N Seth; M L Suri
Journal:  J Neurol Neurosurg Psychiatry       Date:  1978-02       Impact factor: 10.154

6.  New method for detection and quantitation of circulating platelet aggregates.

Authors:  R D Maca; G L Fry; J C Hoak
Journal:  Microvasc Res       Date:  1972-10       Impact factor: 3.514

7.  Increased platelet aggregates in patients with transient ischemic attacks.

Authors:  K K Wu; J C Hoak
Journal:  Stroke       Date:  1975 Sep-Oct       Impact factor: 7.914

8.  A randomized trial of aspirin and sulfinpyrazone in threatened stroke.

Authors: 
Journal:  N Engl J Med       Date:  1978-07-13       Impact factor: 91.245

9.  Platelet hyperaggregability and thrombosis in patients with thrombocythemia.

Authors:  K K Wu
Journal:  Ann Intern Med       Date:  1978-01       Impact factor: 25.391

10.  Elevated beta-thromboglobulin levels and circulating platelet aggregates in diabetic microangiopathy.

Authors:  F E Preston; J D Ward; B H Marcola; N R Porter; W R Timperley; B C O'Malley
Journal:  Lancet       Date:  1978-02-04       Impact factor: 79.321
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  1 in total

1.  Naudicelle and platelet reactivity in TIA patients.

Authors:  M Prencipe; S Paolucci; L Morelli; L Caprino
Journal:  Ital J Neurol Sci       Date:  1982-12
  1 in total

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