Literature DB >> 7340829

Identification of fatty acid synthetase messenger RNA on free polyribosomes isolated from lactating rabbit mammary gland.

M Antoniou, R Craig, R Dils.   

Abstract

The synthesis of fatty acid synthetase on free polyribosomes from lactating rabbit mammary gland was demonstrated by using polyribosomes run-off techniques and immunochemical identification of products with synthetase antiserum. Several reproducible and discrete immunoprecipitable polypeptides were observed which were within the molecular-weight range of the synthetase subunit (235 000--252 000), as well as several of lower molecular weight.

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Year:  1981        PMID: 7340829      PMCID: PMC1163437          DOI: 10.1042/bj1990789

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  22 in total

Review 1.  Control mechanisms in the synthesis of saturated fatty acids.

Authors:  K Bloch; D Vance
Journal:  Annu Rev Biochem       Date:  1977       Impact factor: 23.643

2.  Distribution of casein mRNA between free and membrane-bound polysomes during induction of lactogenesis in the rabbit.

Authors:  L M Houdebine
Journal:  Mol Cell Endocrinol       Date:  1977-04       Impact factor: 4.102

3.  Regulation of fatty acid synthetase in perinatal chicks. Identification of polysomes synthesizing fatty acid synthetase.

Authors:  Z E Zehner; V C Joshi; S J Wakil
Journal:  J Biol Chem       Date:  1977-10-25       Impact factor: 5.157

4.  Translation and characterization of the fatty acid synthetase messenger RNA.

Authors:  C M Nepokroeff; J W Porter
Journal:  J Biol Chem       Date:  1978-04-10       Impact factor: 5.157

5.  Mammalian fatty acid synthetase: evidence for subunit identity and specific removal of the thioesterase component using elastase digestion.

Authors:  P Guy; S Law; G Hardie
Journal:  FEBS Lett       Date:  1978-10-01       Impact factor: 4.124

6.  Molecular weight and subunit size of rabbit mammary-gland fatty acid synthetase.

Authors:  I Grunnet; J Knudsen
Journal:  Biochem J       Date:  1978-09-01       Impact factor: 3.857

7.  Purification and physicochemical properties of fatty acid synthetase and acetyl-CoA carboxylase from lactating rabbit mammary gland.

Authors:  D G Hardie; P Cohen
Journal:  Eur J Biochem       Date:  1978-12-01

8.  Guinea-pig milk-protein synthesis. Isolation and characterization of messenger ribonucleic acids from lactating mammary gland and identification of caseins and pre-alpha-lactalbumin as translation products in heterologous cell-free systems.

Authors:  R K Craig; P A Brown; O S Harrison; D McIlreavy; P N Campbell
Journal:  Biochem J       Date:  1976-10-15       Impact factor: 3.857

9.  Regulation of enzyme turnover during tissue differention. Studies on the effects of hormones on the turnover of fatty acid synthetase in rabbit mammary gland in organ culture.

Authors:  B K Speake; R Dils; R J Mayer
Journal:  Biochem J       Date:  1975-05       Impact factor: 3.857

10.  Regulation of enzyme turnover during tissue differentiation. Interactions of insulin, prolactin and cortisol in controlling the turnover of fatty acid synthetase in rabbit mammary gland in organ culture.

Authors:  B K Speake; R Dils; R J Mayer
Journal:  Biochem J       Date:  1976-02-15       Impact factor: 3.857

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