| Literature DB >> 7336960 |
Abstract
Vascular permeability, platelet function, blood coagulation and fibrinolytic activity were examined in Sprague-Dawley male rats given 1.20% butylated hydroxytoluene (BHT) in the diet for 1 week. BHT significantly increased the leakage of Evans blue from blood into epididymus. BHT inhibited the ADP-induced platelet aggregation and decreased the platelet factor 3 availability. Plasma prothrombin, factors IX, X, VII and VIII were decreased in rats given BHT. Fibrinolytic activity was little influenced by BHT-feeding.Entities:
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Year: 1981 PMID： 7336960 DOI： 10.1111/j.1600-0773.1981.tb00864.x
Source DB: PubMed Journal: Acta Pharmacol Toxicol (Copenh) ISSN： 0001-6683