Literature DB >> 7336919

Radiation-induced parathyroid adenomas and thyroid tumors in rats.

M Fjälling, G Hansson, I Hedman, I Ragnhult, L E Tisell.   

Abstract

Parathyroid morphology was studied in 45 irradiated and 37 control rats. The irradiated rats received a single parathyroid dose of about 6.5 gray. The rats were killed and autopsied 14 months later. The radiation resulted in fibrosis and depression in weight of the parathyroids. In irradiated rats eleven parathyroid adenomas and four thyroid tumors were found. In control rats no tumor occurred in either parathyroid or thyroid glands. All irradiated rats, including those with a parathyroid adenoma, were normocalcemic.

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Year:  1981        PMID: 7336919     DOI: 10.1111/j.1699-0463.1981.tb00241.x

Source DB:  PubMed          Journal:  Acta Pathol Microbiol Scand A        ISSN: 0365-4184


  1 in total

1.  Two Cases of Metastatic Parathyroid Carcinoma in Male C3H Mice Following Irradiation.

Authors:  Yasushi Ohmachi; Midori Yoshida; Toshiaki Ogiu
Journal:  J Toxicol Pathol       Date:  2013-12-26       Impact factor: 1.628

  1 in total

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