Literature DB >> 733681

Herbal medicines and veno-occlusive disease in India.

D V Datta, M S Khuroo, A R Mattocks, B K Aikat, P N Chhuttani.   

Abstract

Six cases are described of veno-occlusive disease (VOD) after medicinal herb ingestion. The herb Heliotropium eichwaldii, taken by three patients, was found to contain the toxic pyrrolizidine alkaloid, heliotrine. Two patients presented with fulminant hepatic failure while the other four patients had a clinical picture suggestive of decompensated cirrhosis. The medical use of this herb may possibly be responsible for a significant proportion of acute and chronic liver disease in India, making it of public health importance.

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Year:  1978        PMID： 733681      PMCID： PMC2425287          DOI： 10.1136/pgmj.54.634.511

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN： 0032-5473            Impact factor:   2.401


  13 in total

1.  Veno-occlusive disease of liver.

Authors:  P S GUPTA; G D GUPTA; M L SHARMA
Journal:  Br Med J       Date:  1963-05-04

2.  Cirrhosis of the liver in Jamaica.

Authors:  G BRAS; S E BROOKS; D C WATLER
Journal:  J Pathol Bacteriol       Date:  1961-10

3.  Cirrhosis of the liver in northern India. A clinicopathologic study.

Authors:  V RAMALINGASWAMI; K L WIG; S K SAMA
Journal:  Arch Intern Med       Date:  1962-09

4.  Senecio poisoning exhibiting as Chiari's syndrome; a report on twelve cases.

Authors:  G SELZER; R G F PARKER
Journal:  Am J Pathol       Date:  1951 Sep-Oct       Impact factor: 4.307

5.  Morphological features of Indian childhood cirrhosis: the spectrum of changes and their significance.

Authors:  B K Aikat; T Bhattacharya; B N Walia
Journal:  Indian J Med Res       Date:  1974-07       Impact factor: 2.375

6.  Toxicology and carcinogenic action of pyrrolizidine alkaloids.

Authors:  R Schoental
Journal:  Cancer Res       Date:  1968-11       Impact factor: 12.701

7.  An outbreak of hepatic veno-occlusive disease in north-western Afghanistan.

Authors:  O Mohabbat; M S Younos; A A Merzad; R N Srivastava; G G Sediq; G N Aram
Journal:  Lancet       Date:  1976-08-07       Impact factor: 79.321

8.  Study of an epidemic of venoocclusive disease in India.

Authors:  R K Tandon; B N Tandon; H D Tandon; M L Bhatia; S Bhargava; P Lal; R R Arora
Journal:  Gut       Date:  1976-11       Impact factor: 23.059

9.  Hepatic veno-occlusive disease originating in Ecuador.

Authors:  C L Lyford; G G Vergara; D D Moeller
Journal:  Gastroenterology       Date:  1976-01       Impact factor: 22.682

10.  Study of an epidemic of jaundice, presumably due to toxic hepatitis, in Northwest India.

Authors:  B N Tandon; L Krishnamurthy; A Koshy; H D Tandon; V Ramalingaswami; J R Bhandari; M M Mathur; P D Mathur
Journal:  Gastroenterology       Date:  1977-03       Impact factor: 22.682
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  6 in total

Review 1.  The harmful potential of herbal and other plant products.

Authors:  R J Huxtable
Journal:  Drug Saf       Date:  1990       Impact factor: 5.606

Review 2.  Morbidity and mortality of portal hypertension.

Authors:  J B Ready; W G Rector
Journal:  Drugs       Date:  1989       Impact factor: 9.546

3.  Herbal tea induced hepatic veno-occlusive disease: quantification of toxic alkaloid exposure in adults.

Authors:  C R Kumana; M Ng; H J Lin; W Ko; P C Wu; D Todd
Journal:  Gut       Date:  1985-01       Impact factor: 23.059

Review 4.  Herbal hepatotoxicity in traditional and modern medicine: actual key issues and new encouraging steps.

Authors:  Rolf Teschke; Axel Eickhoff
Journal:  Front Pharmacol       Date:  2015-04-23       Impact factor: 5.810

Review 5.  Scientific and Regulatory Perspectives in Herbal and Dietary Supplement Associated Hepatotoxicity in the United States.

Authors:  Mark I Avigan; Robert P Mozersky; Leonard B Seeff
Journal:  Int J Mol Sci       Date:  2016-03-03       Impact factor: 5.923

6.  Hepatotoxic pyrrolizidine alkaloids induce DNA damage response in rat liver in a 28-day feeding study.

Authors:  Johanna Ebmeyer; Josef Daniel Rasinger; Jan G Hengstler; Dirk Schaudien; Otto Creutzenberg; Alfonso Lampen; Albert Braeuning; Stefanie Hessel-Pras
Journal:  Arch Toxicol       Date:  2020-05-17       Impact factor: 5.153
  6 in total

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