[Neurochemical data concerning glial tumors. Contribution of the estimation of the G.F.A. protein to the diagnosis and prognosis of gliomas (author's transl)].

The Glial Fibrillary Acidic (G.F.A.) protein is a specific component of the gliofilaments present in the astrocytes. Its immunochemical determination on tumor fragments obtained at surgery has permitted to draw clinico-biochemical correlations between the G.F.A. content of a glioma and its histological grade. The more a glioma is dedifferentiated, the lower is its content of G.F.A. This determination is a biochemical index of dedifferentiation. However, its pronostic value is not established yet.